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Recombinant human NXT1 protein

CAT: 0112-ATGP1045-010Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP1045-010Size:10 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NXT1 functions as a nuclear export factor in both RAN (Ras-related nuclear protein) and CRM1 (required for chromosome region maintenance) dependent pathways. It is found to stimulate the export of u1 snRNA in RAN- and CRM1-dependent pathways and the export of tRNA and mRNA in a CRM1-independent pathway. This protien heterodimerizes with Tap protein and may regulate the ability of Tap protein to mediate nuclear mRNA export. Recombinant human NXT1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Product Name Alternative
NTF2-related export protein 1, MTR2, P15
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by BCA assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
18 kDa (160aa) confirmed by MALDI-TOF
Additionnal Information
NXT1, NTF2-related export protein 1, MTR2, P15, ATGP1045-10 µg, ATGP1045-20 µg, ATGP1045-50 µg, ATGP1045-100 µg, ATGP1045-250 µg, ATGP1045-500 µg, ATGP1045-1 mg, ATGP1045-10, ATGP1045-20, ATGP1045-50, ATGP1045-100, ATGP1045-250, ATGP1045-500, ATGP1045-1
References & Citations
Black B.E., et al. (1999) Mol. Cell. Biol. 19:8616-8624; ; Ossareh-Nazari B., et al. (2000) Mol. Cell. Biol. 20:4562-4571
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl
Scientific Category
Signal Transduction
NCBI Accession Number
NP_037380
Uniprot Accession Number
Q9UKK6
Species
Human
AA Sequence
MASVDFKTYV DQACRAAEEF VNVYYTTMDK RRRLLSRLYM GTATLVWNGN AVSGQESLSE FFEMLPSSEF QISVVDCQPV HDEATPSQTT VLVVICGSVK FEGNKQRDFN QNFILTAQAS PSNTVWKIAS DCFRFQDWAS

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