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Recombinant human MKK3 protein

CAT: 0112-ATGP0999-050Size: 50 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP0999-050Size:50 µg
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Description
MAP2K3, also known as dual specificity mitogen-activated protein kinase kinase 3, is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Recombinant human MAP2K3 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Product Name Alternative
Dual specificity mitogen-activated protein kinase kinase 3, MAPKK3, MEK3, MKK3, PRKMK3
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
38.3 kDa (338aa) confirmed by MALDI-TOF
Additionnal Information
MKK3, Dual specificity mitogen-activated protein kinase kinase 3, MAPKK3, MEK3, MKK3, PRKMK3, ATGP0999-10 µg, ATGP0999-20 µg, ATGP0999-50 µg, ATGP0999-100 µg, ATGP0999-250 µg, ATGP0999-500 µg, ATGP0999-1 mg, ATGP0999-10, ATGP0999-20, ATGP0999-50, ATGP0999-100, ATGP0999-250, ATGP0999-500, ATGP0999-1
References & Citations
Rampoldi L., et al. (1997) Cytogenet Cell Genet. 78 (3-4) :301-3.; ; Barr AJ., et al. (2002) Biochem Biophys Res Commun. 293 (1) :647-52.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
Scientific Category
Immunology
NCBI Accession Number
NP_002747.2
Uniprot Accession Number
P46734
Species
Human
AA Sequence
MSKPPAPNPT PPRNLDSRTF ITIGDRNFEV EADDLVTISE LGRGAYGVVE KVRHAQSGTI MAVKRIRATV NSQEQKRLLM DLDINMRTVD CFYTVTFYGA LFREGDVWIC MELMDTSLDK FYRKVLDKNM TIPEDILGEI AVSIVRALEH LHSKLSVIHR DVKPSNVLIN KEGHVKMCDF GISGYLVDSV AKTMDAGCKP YMAPERINPE LNQKGYNVKS DVWSLGITMI EMAILRFPYE SWGTPFQQLK QVVEEPSPQL PADRFSPEFV DFTAQCLRKN PAERMSYLEL MEHPFFTLHK TKKTDIAAFV KEILGEDS

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