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Recombinant human MORF4L2 protein

CAT: 0112-ATGP0987-100Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP0987-100Size:100 µg
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Description
MORF4L2 is a member of the mortality factor (MORF) family of transcriptional regulator that is involved in cell growth, regulation and senescence. This protein localizes to the nucleus, and it has a protein kinase C phosphorylation site as well as a tyrosine phosphorylation site. It interacts with the Rb tumor suppressor through its helix-loop-helix and leucine zipper regions. It also has histone deacetylase activity and can either repress or promote the activity of the B-Myb promoter depending on the tissue. Recombinant human MORF4L2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Product Name Alternative
Mortality factor 4-like protein 2, KIAA0026, MORFL2, MRGX
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
34.4 kDa (308aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
Additionnal Information
MORF4L2, Mortality factor 4-like protein 2, KIAA0026, MORFL2, MRGX, ATGP0987-10 µg, ATGP0987-20 µg, ATGP0987-50 µg, ATGP0987-100 µg, ATGP0987-250 µg, ATGP0987-500 µg, ATGP0987-1 mg, ATGP0987-10, ATGP0987-20, ATGP0987-50, ATGP0987-100, ATGP0987-250, ATGP0987-500, ATGP0987-1
References & Citations
Nomura N., et al. (1995), DNA Res.. 1: 27-35.; ; Tominaga K, et al. (2003) . J. Biol. Chem.. 278: 49618-49624.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 1mM DTT
Scientific Category
Cancer
NCBI Accession Number
NP_036418
Uniprot Accession Number
Q15014
Species
Human
AA Sequence
MSSRKQGSQP RGQQSAEEEN FKKPTRSNMQ RSKMRGASSG KKTAGPQQKN LEPALPGRWG GRSAENPPSG SVRKTRKNKQ KTPGNGDGGS TSEAPQPPRK KRARADPTVE SEEAFKNRME VKVKIPEELK PWLVEDWDLV TRQKQLFQLP AKKNVDAILE EYANCKKSQG NVDNKEYAVN EVVAGIKEYF NVMLGTQLLY KFERPQYAEI LLAHPDAPMS QVYGAPHLLR LFVRIGAMLA YTPLDEKSLA LLLGYLHDFL KYLAKNSASL FTASDYKVAS AEYHRKAL

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