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Recombinant human S100A5 protein

CAT: 0112-ATGP0957-020Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP0957-020Size:20 µg
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Description
S100 calcium binding protein A5, also known as S100A5, is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100A5 has a Ca2+ affinity 20- to 100-fold higher than the other S100 proteins studied under identical conditions. This protein also binds Zn2+ and Cu2+, and Cu2+ strongly which impairs the binding of Ca2+. S100A5 is expressed in very restricted regions of the adult brain. Recombinant human S100A5 protien, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Name Alternative
S100 calcium binding protein A5, S100D
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
12.9 kDa (112aa) confirmed by MALDI-TOF
Additionnal Information
S100A5, S100 calcium binding protein A5, S100D, ATGP0957-10 µg, ATGP0957-20 µg, ATGP0957-50 µg, ATGP0957-100 µg, ATGP0957-250 µg, ATGP0957-500 µg, ATGP0957-1 mg, ATGP0957-10, ATGP0957-20, ATGP0957-50, ATGP0957-100, ATGP0957-250, ATGP0957-500, ATGP0957-1
References & Citations
Schafer BW., et al. (1996) Trends Biochem Sci. 21 (4) :134-40.; ; Schafer BW., et al. (2000) J Biol Chem. 275 (39) :30623-30
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 30% glycerol, 0.1M NaCl, 0.1mM PMSF
Scientific Category
Signal Transduction
NCBI Accession Number
NP_002953
Uniprot Accession Number
P33763
Species
Human
AA Sequence
MGSSHHHHHH SSGLVPRGSH METPLEKALT TMVTTFHKYS GREGSKLTLS RKELKELIKK ELCLGEMKES SIDDLMKSLD KNSDQEIDFK EYSVFLTMLC MAYNDFFLED NK

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