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Recombinant human MESDC2 protein

CAT: 0112-ATGP0933-500Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP0933-500Size:500 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MESDC2, also known as Mesoderm development candidate 2, is required for formation of the primitive streak and mesoderm during embryogenesis. This protein binds to the Wnt co-receptors LRP5 and LRP6 in the endoplasmic reticulum and is required for their proper folding and cell surface expression. Recombinant human MESDC2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Product Name Alternative
LDLR chaperone MESD, BOCA, KIAA0081, MESD
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by BCA assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
24.9 kDa (222aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
Additionnal Information
MESDC2, LDLR chaperone MESD, BOCA, KIAA0081, MESD, ATGP0933-10 µg, ATGP0933-20 µg, ATGP0933-50 µg, ATGP0933-100 µg, ATGP0933-250 µg, ATGP0933-500 µg, ATGP0933-1 mg, ATGP0933-10, ATGP0933-20, ATGP0933-50, ATGP0933-100, ATGP0933-250, ATGP0933-500, ATGP0933-1
References & Citations
Kohler C, et al. (2006) . J Struct Funct Genomics, 7:131-8.; ; Wines ME., et al. (2001) . Genomics., 72:88-98.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 20% Glycerol
Scientific Category
Heat Shock Proteins
NCBI Accession Number
NP_055969
Uniprot Accession Number
Q14696
Species
Human
AA Sequence
AEGSPGTPD ESTPPPRKKK KDIRDYNDAD MARLLEQWEK DDDIEEGDLP EHKRPSAPVD FSKIDPSKPE SILKMTKKGK TLMMFVTVSG SPTEKETEEI TSLWQGSLFN ANYDVQRFIV GSDRAIFMLR DGSYAWEIKD FLVGQDRCAD VTLEGQVYPG KGGGSKEKNK TKQDKGKKKK EGDLKSRSSK EENRAGNKRE DL

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