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Recombinant human GRAP2 protein

CAT: 0112-ATGP0888-010Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP0888-010Size:10 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GRAP2, also known as GADS, is a member of the GRB2/Sem5/Drk family. This member is an adaptor-like protein involved in leukocyte-specific protein-tyrosine kinase signaling. Like its related family member, GRB2-related adaptor protein (GRAP), this protein contains an SH2 domain flanked by two SH3 domains. This protein interacts with other proteins, such as GRB2-associated binding protein 1 (GAB1) and the SLP-76 leukocyte protein (LCP2), through its SH3 domains. Recombinant human GRAP2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Name Alternative
GRB2-related adapter protein 2, GADS, GRB2L, GRBLG, GrbX, Grf40, GRID, GRPL, Mona, P38
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
40 kDa (350aa) confirmed by MALDI-TOF
Additionnal Information
GRAP2, GRB2-related adapter protein 2, GADS, GRB2L, GRBLG, GrbX, Grf40, GRID, GRPL, Mona, P38, ATGP0888-10 µg, ATGP0888-20 µg, ATGP0888-50 µg, ATGP0888-100 µg, ATGP0888-250 µg, ATGP0888-500 µg, ATGP0888-1 mg, ATGP0888-10, ATGP0888-20, ATGP0888-50, ATGP0888-100, ATGP0888-250, ATGP0888-500, ATGP0888-1
References & Citations
Ludwig L., et al. (2009) Cancer Lett. 275 (2) :194-7.; ; Chang TW., et al. (2008) Oncogene. 27 (3) :332-8.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 5mM DTT, 1mM EDTA, 30% glycerol
Scientific Category
Cancer
NCBI Accession Number
NP_004801
Uniprot Accession Number
O75791
Species
Human
AA Sequence
MGSSHHHHHH SSGLVPRGSH MEAVAKFDFT ASGEDELSFH TGDVLKILSN QEEWFKAELG SQEGYVPKNF IDIQFPKWFH EGLSRHQAEN LLMGKEVGFF IIRASQSSPG DFSISVRHED DVQHFKVMRD NKGNYFLWTE KFPSLNKLVD YYRTNSISRQ KQIFLRDRTR EDQGHRGNSL DRRSQGGPHL SGAVGEEIRP SMNRKLSDHP PTLPLQQHQH QPQPPQYAPA PQQLQQPPQQ RYLQHHHFHQ ERRGGSLDIN DGHCGTGLGS EMNAALMHRR HTDPVQLQAA GRVRWARALY DFEALEDDEL GFHSGEVVEV LDSSNPSWWT GRLHNKLGLF PANYVAPMTR

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