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Recombinant human SDCBP protein

CAT: 0112-ATGP0809-500Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP0809-500Size:500 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SDCBP, also known as Syntenin1, is a multifunctional intracellular adapter protein. This protein contains tandemly repeated PDZ domains that react with the FYA (phe-tyr-ala) carboxyterminal amino acid sequence of the syndecans. It is involved in organization of protein complexes in the plasma membranes, regulation of B-cell development, activation of transcription factors, intracellular trafficking and cell-surface targeting, synaptic transmission, and axonal outgrowth. Recombinant human SDCBP protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Product Name Alternative
Syntenin-1, MDA-9, ST1, SYCL, TACIP18
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 90% by SDS-PAGE
Molecular Weight
34.6 kDa (318aa) confirmed by MALDI-TOF
Additionnal Information
SDCBP, Syntenin-1, MDA-9, ST1, SYCL, TACIP18, ATGP0809-10 µg, ATGP0809-20 µg, ATGP0809-50 µg, ATGP0809-100 µg, ATGP0809-250 µg, ATGP0809-500 µg, ATGP0809-1 mg, ATGP0809-10, ATGP0809-20, ATGP0809-50, ATGP0809-100, ATGP0809-250, ATGP0809-500, ATGP0809-1
References & Citations
Lee CH., et al. (2010) Comp Biochem Physiol C Toxicol Pharmacol. 152 (2) :195-201.; ; Fisher PB., et al (2008) Cancer Res. 68 (9) :3087-93.
Other References
Meyer A et al., Metabolic reprogramming by Syntenin-1 directs RA FLS and endothelial cell-mediated inflammation and angiogenesis. (Cell Mol Immunol. 2024) {https://pubmed.ncbi.nlm.nih.gov/38105293/}; ; Zack SR et al., Notch ligands are biomarkers of anti-TNF response in RA patients. (Angiogenesis. 2024) {https://pubmed.ncbi.nlm.nih.gov/37796367/}
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 100 mM NaCl, 40% glycerol
Scientific Category
Neuroscience
NCBI Accession Number
NP_005616.2
Uniprot Accession Number
O00560
Species
Human
AA Sequence
MSLYPSLEDL KVDKVIQAQT AFSANPANPA ILSEASAPIP HDGNLYPRLY PELSQYMGLS LNEEEIRANV AVVSGAPLQG QLVARPSSIN YMVAPVTGND VGIRRAEIKQ GIREVILCKD QDGKIGLRLK SIDNGIFVQL VQANSPASLV GLRFGDQVLQ INGENCAGWS SDKAHKVLKQ AFGEKITMTI RDRPFERTIT MHKDSTGHVG FIFKNGKITS IVKDSSAARN GLLTEHNICE INGQNVIGLK DSQIADILST SGTVVTITIM PAFIFEHIIK RMAPSIMKSL MDHTIPEV

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