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Recombinant human ARF6 protein

CAT: 0112-ATGP0802-500Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP0802-500Size:500 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ADP-ribosylation factor 6, also known as ARF6, is a member of the ADP ribosylation factor family of GTP-binding proteins. It is localized to the plasma membrane, and regulates vesicular trafficking, remodelling of membrane lipids, and signaling pathways that lead to actin remodeling. Additionally, ARF6 play a central role in maintenance of organelle integrity, assembly of coat proteins and activation of phospholipase D. Recombinant human ARF6 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Name Alternative
ADP-ribosylation factor 6
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
22.2 kDa (195aa) confirmed by MALDI-TOF
Additionnal Information
ARF6, ATGP0802-10 µg, ATGP0802-20 µg, ATGP0802-50 µg, ATGP0802-100 µg, ATGP0802-250 µg, ATGP0802-500 µg, ATGP0802-1 mg, ATGP0802-10, ATGP0802-20, ATGP0802-50, ATGP0802-100, ATGP0802-250, ATGP0802-500, ATGP0802-1
References & Citations
Amor J C., et al. (1994) Nature. 372:704-708.; ; Randazzo P A., et al. (1994) J Biol Chem. 269:29490-29494.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 20% glycerol, 0.2mM PMSF
Scientific Category
Signal Transduction
NCBI Accession Number
NP_001654
Uniprot Accession Number
P62330
Species
Human
AA Sequence
MGKVLSKIFG NKEMRILMLG LDAAGKTTIL YKLKLGQSVT TIPTVGFNVE TVTYKNVKFN VWDVGGQDKI RPLWRHYYTG TQGLIFVVDC ADRDRIDEAR QELHRIINDR EMRDAIILIF ANKQDLPDAM KPHEIQEKLG LTRIRDRNWY VQPSCATSGD GLYEGLTWLT SNYKS

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