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Recombinant human WDR5 protein

CAT: 0112-ATGP0632-500Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP0632-500Size:500 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
WDR5, also designated BMP-2-induced gene 3 kb or BIG-3, belongs to the family of WD-40 repeat proteins, and is essential for vertebrate development, Hox gene activation and global H3K4 trimethylation. This protein is expressed in osteoblasts, chondrocytes, osteocytes and marrow stromal cells. WDR5 may play a role in its function of accelerating osteoblast differentiation. Recombinant human WDR5 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Name Alternative
WD repeat-containing protein 5, BIG-3, SWD3, WD repeat-containing protein 5, BIG 3, WDR 5, WDR-5
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
38.8 kDa (354aa) confirmed by MALDI-TOF
Additionnal Information
WDR5, WD repeat-containing protein 5, BIG-3, SWD3, WD repeat-containing protein 5, BIG 3, WDR 5, WDR-5, ATGP0632-10 µg, ATGP0632-20 µg, ATGP0632-50 µg, ATGP0632-100 µg, ATGP0632-250 µg, ATGP0632-500 µg, ATGP0632-1 mg, ATGP0632-10, ATGP0632-20, ATGP0632-50, ATGP0632-100, ATGP0632-250, ATGP0632-500, ATGP0632-1
References & Citations
Yokoyama., et al. (2004) Mol Cell Biol. 24 (13) :5639-49. ; ; Gori F., et al. (2001) J Biol Chem. 276 (49) :46515-22. ;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 2mM DTT, 0.1M NaCl.
Scientific Category
Epigenomics (Transcription & Translation)
NCBI Accession Number
NP_438172.1
Uniprot Accession Number
P61964
Species
Human
AA Sequence
MATEEKKPET EAARAQPTPS SSATQSKPTP VKPNYALKFT LAGHTKAVSS VKFSPNGEWL ASSSADKLIK IWGAYDGKFE KTISGHKLGI SDVAWSSDSN LLVSASDDKT LKIWDVSSGK CLKTLKGHSN YVFCCNFNPQ SNLIVSGSFD ESVRIWDVKT GKCLKTLPAH SDPVSAVHFN RDGSLIVSSS YDGLCRIWDT ASGQCLKTLI DDDNPPVSFV KFSPNGKYIL AATLDNTLKL WDYSKGKCLK TYTGHKNEKY CIFANFSVTG GKWIVSGSED NLVYIWNLQT KEIVQKLQGH TDVVISTACH PTENIIASAA LENDKTIKLW KSDC

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