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Recombinant human CAB39 protein

CAT: 0112-ATGP0617-250Size: 250 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP0617-250Size:250 µg
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Description
Calcium binding protein 39, also known as CAB39, is a 40-kDa protein that, together with the STE20-related adaptor-alpha (STRAD alpha) pseudo kinase, forms a regulatory complex capable of stimulating the activity of the LKB1 tumor suppressor protein kinase. Also CAB39 may function as a scaffolding component of the STK11/STRAD complex and regulates STK11 activity and cellular localization. Recombinant human CAB39, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques
Product Name Alternative
Calcium binding protein 39, CGI-66, MO25, Calcium binding protein 39, CAB 39, CAB-39, MO 25, MO-25, FLJ22682
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
42 kDa (361aa) confirmed by MALDI-TOF
Additionnal Information
CAB39, Calcium binding protein 39, CGI-66, MO25, Calcium binding protein 39, CAB 39, CAB-39, MO 25, MO-25, FLJ22682, ATGP0617-10 µg, ATGP0617-20 µg, ATGP0617-50 µg, ATGP0617-100 µg, ATGP0617-250 µg, ATGP0617-500 µg, ATGP0617-1 mg, ATGP0617-10, ATGP0617-20, ATGP0617-50, ATGP0617-100, ATGP0617-250, ATGP0617-500, ATGP0617-1
References & Citations
Baas AF., et al. (2004) Trends Cell Biol. 14 (6) :312-9.; ; Boudeau J., et al. (2003) EMBO J. 22 (19) :5102-14.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol
Scientific Category
Cancer
NCBI Accession Number
NP_057373
Uniprot Accession Number
Q9Y376
Species
Human
AA Sequence
MGSSHHHHHH SSGLVPRGSH MPFPFGKSHK SPADIVKNLK ESMAVLEKQD ISDKKAEKAT EEVSKNLVAM KEILYGTNEK EPQTEAVAQL AQELYNSGLL STLVADLQLI DFEGKKDVAQ IFNNILRRQI GTRTPTVEYI CTQQNILFML LKGYESPEIA LNCGIMLREC IRHEPLAKII LWSEQFYDFF RYVEMSTFDI ASDAFATFKD LLTRHKLLSA EFLEQHYDRF FSEYEKLLHS ENYVTKRQSL KLLGELLLDR HNFTIMTKYI SKPENLKLMM NLLRDKSRNI QFEAFHVFKV FVANPNKTQP ILDILLKNQA KLIEFLSKFQ NDRTEDEQFN DEKTYLVKQI RDLKRPAQQE A