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Recombinant human RAN protein

CAT: 0112-ATGP0590-010Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP0590-010Size:10 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RAN, member RAS oncogene family, also known as RAN, is a small GTPase of the Ras superfamily that controls nucleocytoplasmic transport. It is involved in the directionality of the process that is regulated by GTP hydrolysis. Ran shuttles between the nucleus and the cytoplasm. unlike many other regulatory GTPases, Ran is not posttranslationally modified so that it can be targeted to the subcellular compartment where it acts. Rather, RanGTP has been thought to be localized by the differential localization of Ran regulators. Recombinant human RAN, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques
Product Name Alternative
RAN member RAS oncogene family, ARA24, Gsp1, TC4, RAN, member RAS oncogene family, Androgen receptor associated protein 24, ARA 24, GTP binding nuclear protein RAN, GTPase Ran, LPS, RAN member RAS oncogene family, Ras like protein TC4, RASL2 8
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
26.5 kDa (236aa) confirmed by MALDI-TOF
Additionnal Information
RAN, RAN member RAS oncogene family, ARA24, Gsp1, TC4, RAN, member RAS oncogene family, Androgen receptor associated protein 24, ARA 24, GTP binding nuclear protein RAN, GTPase Ran, LPS, RAN member RAS oncogene family, Ras like protein TC4, RASL2 8, ATGP0590-10 µg, ATGP0590-20 µg, ATGP0590-50 µg, ATGP0590-100 µg, ATGP0590-250 µg, ATGP0590-500 µg, ATGP0590-1 mg, ATGP0590-10, ATGP0590-20, ATGP0590-50, ATGP0590-100, ATGP0590-250, ATGP0590-500, ATGP0590-1
References & Citations
Woo IS., et al. (2008) Apoptosis. 13 (10) :1223-31.; ; Ren M., et al. (1994) Mol Cell biol. 14 (6) :4216-24.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol
Scientific Category
Signal Transduction
NCBI Accession Number
NP_006316
Uniprot Accession Number
P62826
Species
Human
AA Sequence
MAAQGEPQVQ FKLVLVGDGG TGKTTFVKRH LTGEFEKKYV ATLGVEVHPL VFHTNRGPIK FNVWDTAGQE KFGGLRDGYY IQAQCAIIMF DVTSRVTYKN VPNWHRDLVR VCENIPIVLC GNKVDIKDRK VKAKSIVFHR KKNLQYYDIS AKSNYNFEKP FLWLARKLIG DPNLEFVAMP ALAPPEVVMD PALAAQYEHD LEVAQTTALP DEDDDL

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