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Recombinant human CERT1 protein

CAT: 0112-ATGP0579-100Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP0579-100Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CERT is a kinase that specifically phosphorylates the N-terminal region of the non-collagenous domain of the alpha 3 chain of type IV collagen, known as the Goodpasture antigen. Goodpasture disease is the result of an autoimmune response directed at this antigen. One isoform of this protein is also involved in ceramide intracellular transport. Recombinant human CERT protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Name Alternative
Ceramide transporter 1, Collagen type IV alpha-3-binding protein, Goodpasture antigen-binding protein, GPBP, START domain-containing protein 11, StARD11, StAR-related lipid transfer protein 11, CERT, COL4A3BP
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
32.9 kDa (290aa) confirmed by MALDI-TOF
Additionnal Information
CERT, ATGP0579-10 µg, ATGP0579-20 µg, ATGP0579-50 µg, ATGP0579-100 µg, ATGP0579-250 µg, ATGP0579-500 µg, ATGP0579-1 mg, ATGP0579-10, ATGP0579-20, ATGP0579-50, ATGP0579-100, ATGP0579-250, ATGP0579-500, ATGP0579-1
References & Citations
Turner N., et al. (1992) J Clin Invest 89 (2) :592-601.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.1M NaCl
Scientific Category
Immunology
NCBI Accession Number
NP_112729
Uniprot Accession Number
Q9Y5P4
Species
Human
AA Sequence
LH WPTSLPSGDA FSSVGTHRFV QKVEEMVQNH MTYSLQDVGG DANWQLVVEE GEMKVYRREV EENGIVLDPL KATHAVKGVT GHEVCNYFWN VDVRNDWETT IENFHVVETL ADNAIIIYQT HKRVWPASQR DVLYLSVIRK IPALTENDPE TWIVCNFSVD HDSAPLNNRC VRAKINVAMI CQTLVSPPEG NQEISRDNIL CKITYVANVN PGGWAPASVL RAVAKREYPK FLKRFTSYVQ EKTAGKPILF

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