Products for Research Use Only
RegisterLogin

Recombinant human S100A8 protein

CAT: 0112-ATGP0524-100Size: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0112-ATGP0524-100Size:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
S100 calcium binding protein A8, also known as MRP8, is a member of the S100 family, EF-hand superfamily of Calcium binding proteins. S100A8 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. It functions both intracellularly and extracellularly, where it binds to RAGE and CD36. Altered expression of this protein is associated with the disease cystic fibrosis. Recombinant human S100A8 was expressed in E. coli and purified by using conventional chromatography techniques.
Product Name Alternative
S100 calcium binding protein A8, Calgranulin-A, MRP-8, CFAG, CAGA, S100 calcium binding protein A8 60B8Ag, AI323541, B8Ag, BEE11, CAGA, Calprotectin L1L subunit, Calprotectin, included, CGLA, Chemotactic cytokine CP-10, CP-10, Cystic fibrosisantigen, L1Ag, Leukocyte L1 complex light chain, MA387, MIF, Migration inhibitory factor-related protein 8, Myeloid-related protein 8, Neutrophil cytosolic 7 kDa protein, NIF, p8, Pro-inflammatory S100 cytokine, Protein S100-A8, S100 calcium binding protein A8 (calgranulin A), S100A8, S100A8/S100A9 complex, included, urinary stone protein band A.
Expression System
E.coli
Antigen Species
Human
Tag
Non-Tagged
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by absorbance at 280 nm)
Purity
> 90% by SDS-PAGE
Molecular Weight
10.8 Da (93aa) confirmed by MALDI-TOF
Additionnal Information
S100A8, S100 calcium binding protein A8, Calgranulin-A, MRP-8, CFAG, CAGA, S100 calcium binding protein A8 60B8Ag, AI323541, B8Ag, BEE11, CAGA, Calprotectin L1L subunit, Calprotectin, included, CGLA, Chemotactic cytokine CP-10, CP-10, Cystic fibrosisantigen, L1Ag, Leukocyte L1 complex light chain, MA387, MIF, Migration inhibitory factor-related protein 8, Myeloid-related protein 8, Neutrophil cytosolic 7 kDa protein, NIF, p8, Pro-inflammatory S100 cytokine, Protein S100-A8, S100 calcium binding protein A8 (calgranulin A), S100A8, S100A8/S100A9 complex, included, urinary stone protein band A., ATGP0524-10 µg, ATGP0524-20 µg, ATGP0524-50 µg, ATGP0524-100 µg, ATGP0524-250 µg, ATGP0524-500 µg, ATGP0524-1 mg, ATGP0524-10, ATGP0524-20, ATGP0524-50, ATGP0524-100, ATGP0524-250, ATGP0524-500, ATGP0524-1
References & Citations
Kerkhoff C., et al. (1999) Biochim. Biophys. 1448 (2) :200-11. ; ; Nacken W., et al. (2003) Biochim. Biophys. 60 (6) :569-80.;
Other References
Kwon CH, et al. S100A8 and S100A9 Promotes Invasion and Migration through p38 Mitogen-Activated Protein kinase-Dependent NF-kB Activation in Gastric Cancer Cells. (Mol Cells. 2013) {https://pubmed.ncbi.nlm.nih.gov/23456298/}; ; Nishikawa Y, et al. Calprotectin Induces IL-6 and MCP-1 Production via Toll-Like Receptor 4 Signaling in Human Gingival Fibroblasts. (J Cell Physiol. 2017) {https://pubmed.ncbi.nlm.nih.gov/27925202/}
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol
Scientific Category
Cancer
NCBI Accession Number
NP_002955.2
Uniprot Accession Number
P05109
Species
Human
AA Sequence
MLTELEKALN SIIDVYHKYS LIKGNFHAVY RDDLKKLLET ECPQYIRKKG ADVWFKELDI NTDGAVNFQE FLILVIKMGV AAHKKSHEES HKE

Related Products

CatalogName
ATGP1085-100Recombinant mouse S100A8 protein
ATGP1085-500Recombinant mouse S100A8 protein
ATGP1085-020Recombinant mouse S100A8 protein
ATGP1078-500Recombinant human S100A3 protein
ATGP1078-100Recombinant human S100A3 protein
ATGP0957-100Recombinant human S100A5 protein
ATGP0543-500Recombinant human S100A9 protein
ATGP0319-500Recombinant human S100A4 protein
ATGP0991-100Recombinant human S100A7 protein
ATGP0967-500Recombinant human S100A6 protein

Alternative Products

CatalogName
NBP2-50570-500ugRecombinant Human S100A8 Protein
PROTP05109-500ugHuman S100A8 Recombinant Protein
OPCD06801-50UGS100A8 Recombinant Protein

Popular Products