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LIN28B cDNA

CAT: 0112-ATGD0297-010Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGD0297-010Size:10 µg
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Description
LIN28B belongs to the lin-28 family, which is characterized by the presence of a cold-shock domain and a pair of CCHC zinc finger domains. This gene is highly expressed in testis, fetal liver, placenta, and in primary human tumors and cancer cell lines. It is negatively regulated by microRNAs that target sites in the 3' UTR, and overexpression of this gene in primary tumors is linked to the repression of let-7 family of microRNAs and derepression of let-7 targets, which facilitates cellular transformation.
Product Name Alternative
Protein lin-28 homolog B, CSDD2
Chromosomal Location
6q21
Antigen Species
Human
Vector Type
PATGen (puc19-derived cloning vector)
Sequence
ATGGCCGAAGGCGGGGCTAGCAAAGGTGGTGGAGAAGAGCCCGGGAAGCTGCCGGAGCCGGCAGAGGAGGAATCCCAGGTTTTGCGCGGAACTGGCCACTGTAAGTGGTTCAATGTGCGCATGGGATTTGGATTCATCTCCATGATAAACCGAGAGGGAAGCCCCTTGGATATTCCAGTCGATGTATTTGTACACCAAAGCAAACTATTCATGGAAGGATTTAGAAGCCTAAAAGAAGGAGAACCAGTGGAATTCACATTTAAAAAATCTTCCAAAGGCCTTGAGTCAATACGGGTAACAGGACCTGGTGGGAGCCCCTGTTTAGGAAGTGAAAGAAGACCCAAAGGGAAGACACTACAGAAAAGAAAACCAAAGGGAGATAGATGCTACAACTGTGGTGGCCTTGATCATCATGCTAAGGAATGTAGTCTACCTCCTCAGCCAAAGAAGTGCCATTACTGTCAGAGCATCATGCACATGGTGGCAAACTGCCCACATAAAAATGTTGCACAGCCACCCGCGAGTTCTCAGGGAAGACAGGAAGCAGAATCCCAGCCATGCACTTCAACTCTCCCTCGAGAAGTGGGAGGCGGGCATGGCTGTACATCACCACCGTTTCCTCAGGAGGCTAGGGCAGAGATCTCAGAACGGTCAGGCAGGTCACCTCAAGAAGCTTCCTCCACGAAGTCATCTATAGCACCAGAAGAGCAAAGCAAAAAGGGGCCTTCAGTTCAAAAAAGGAAAAAGACATAA
Additionnal Information
LIN-28B, LIN 28B, LIN28B, Protein lin-28 homolog B, CSDD2, ATGD0297-10 µg, ATGD0297-20 µg, ATGD0297-50 µg, ATGD0297-100 µg, ATGD0297-250 µg, ATGD0297-500 µg, ATGD0297-1 mg, ATGD0297-010, ATGD0297-020, ATGD0297-050, ATGD0297-100, ATGD0297-250, ATGD0297-500, ATGD0297-01M
Storage Conditions
Store the plasmid at -20C.
Formulation
Lyophilized
Scientific Category
Cancer
Omim
611044
NCBI Accession Number
NP_001004317.1
Species
Human
Preparation
1. Centrifuge at 7000rpm for 1 minute.; ;2. Carefully open the vial and add 100 µL of sterile water to dissolve the DNA.; ; Each tube contains approximately 10 µg of lyophilized plasmid.
RNA Reference
NM_001004317.3
DNA Size
753bp

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