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NRGN cDNA

CAT: 0112-ATGD0219-010Size: 10 µgDry Ice: NoHazardous: No
CAT#:0112-ATGD0219-010Size:10 µg
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Description
Neurogranin (NRGN) is the human homolog of the neuron-specific rat RC3/neurogranin gene. This gene encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium. The NRGN gene contains four exons and three introns. The exons 1 and 2 encode the protein and exons 3 and 4 contain untranslated sequences. It is suggested that the NRGN is a direct target for thyroid hormone in human brain, and that control of expression of this gene could underlay many of the consequences of hypothyroidism on mental states during development as well as in adult subjects.
Product Name Alternative
Neurogranin, NRGN, HNG, RC3
Chromosomal Location
11q24
Antigen Species
Human
Vector Type
PATGen (puc19-derived cloning vector)
Sequence
ATGGACTGCTGCACCGAGAACGCCTGCTCCAAGCCGGACGACGACATTCTAGACATCCCGCTGGACGATCCCGGCGCCAACGCGGCCGCCGCCAAAATCCAGGCGAGTTTTCGGGGCCACATGGCGCGGAAGAAGATAAAGAGCGGAGAGCGCGGCCGGAAGGGCCCGGGCCCTGGGGGGCCTGGCGGAGCTGGGGTGGCCCGGGGAGGCGCGGGCGGCGGCCCCAGCGGAGACTAG
Additionnal Information
Neurogranin, NRGN, HNG, RC3, ATGD0219-10 µg, ATGD0219-20 µg, ATGD0219-50 µg, ATGD0219-100 µg, ATGD0219-250 µg, ATGD0219-500 µg, ATGD0219-1 mg, ATGD0219-010, ATGD0219-020, ATGD0219-050, ATGD0219-100, ATGD0219-250, ATGD0219-500, ATGD0219-01M
Storage Conditions
Store the plasmid at -20C.
Formulation
Lyophilized
Scientific Category
Neuroscience
Omim
602350
NCBI Accession Number
NP_001119653.1
Species
Human
Preparation
1. Centrifuge at 7000rpm for 1 minute.; ;2. Carefully open the vial and add 100 µL of sterile water to dissolve the DNA.; ; Each tube contains approximately 10 µg of lyophilized plasmid.
RNA Reference
NM_001126181.1
DNA Size
237bp
Vector Description
This shuttle vector contains the complete ORF. It is inseted BamH I to Xho I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector.

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