DYNLL1 cDNA

• Description:

  DYNLL1, also known as DLC8 or PIN (protein inhibitor of neuronal nitric oxide synthase), has been identified as a protein that interacts with NOS1 resulting in NOS1 inhibition. Binding of this protein destabilizes NOS1 (Neuronal nitric oxide synthase) dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity. DYNLL1 is a ubiquitously expressed protein that exhibits high expression in testis and moderate expression in brain.

• Product Name Alternative:

  DLC1, DLC8, DNCL1, DNCLC1, hdlc1, LC8, LC8a, PIN

• Chromosomal Location:

  12q24.23

• Antigen Species:

  Human

• Vector Type:

  PATGen (puc19-derived cloning vector)

• Sequence:

  ATGTGCGACC GAAAGGCCGT GATCAAAAAT GCGGACATGT CGGAAGAGAT GCAACAGGAC TCGGTGGAGT GCGCTACTCA GGCGCTGGAG AAATACAACA TAGAGAAGGA CATTGCGGCT CATATCAAGA AGGAATTTGA CAAGAAGTAC AATCCCACCT GGCATTGCAT CGTGGGGAGG AACTTCGGTA GTTATGTGAC ACATGAAACC AAACACTTCA TCTACTTCTA CCTGGGCCAA GTGGCCATTC TTCTGTTCAA ATCTGGTTAA

• Additionnal Information:

  DYNLL1, DLC1, DLC8, DNCL1, DNCLC1, hdlc1, LC8, LC8a, PIN, DYNLL1, ATGD0092-10 µg, ATGD0092-20 µg, ATGD0092-50 µg, ATGD0092-100 µg, ATGD0092-250 µg, ATGD0092-500 µg, ATGD0092-1 mg, ATGD0092-10, ATGD0092-20, ATGD0092-50, ATGD0092-100, ATGD0092-250, ATGD0092-500, ATGD0092-1

• Storage Conditions:

  Store the plasmid at -20C.

• Formulation:

  Lyophilized

• Scientific Category:

  Cancer

• Omim:

  601562

• NCBI Accession Number:

  NP_001032583.1

• Species:

  Human

• Preparation:

  1. Centrifuge at 7000rpm for 1 minute.; ;2. Carefully open the vial and add 100 µL of sterile water to dissolve the DNA.; ; Each tube contains approximately 10 µg of lyophilized plasmid.

• RNA Reference:

  NM_001037494.1

• DNA Size:

  270bp

• Vector Description:

  This shuttle vector contains the complete ORF. It is inseted BamH I to Xho I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector.