BAG4 cDNA

CAT: 0112-ATGD0089-010Size: 10 µgDry Ice: NoHazardous: No
CAT#:0112-ATGD0089-010Size:10 µg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BAG4 is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. This protein was found to be associated with the death domain of tumor necrosis factor receptor type 1 (TNF-R1) and death receptor-3 (DR3), and thereby negatively regulates downstream cell death signaling. The regulatory role of this protein in cell death was demonstrated in epithelial cells which undergo apoptosis while integrin mediated matrix contacts are lost. Alternatively spliced transcript variants encoding distinct isoforms have been identified.
Product Name Alternative
BAG-4, SODD, BAG family molecular chaperone regulator 4, BAG cochaperone 4, BCL2 associated athanogene 4
Chromosomal Location
8p11.23
Antigen Species
Human
Vector Type
PATGen (puc19-derived cloning vector)
Sequence
ATGTCGGCCC TGAGGCGCTC GGGCTACGGC CCCAGTGACG GTCCGTCCTA CGGCCGCTAC TACGGGCCTG GGGGTGGAGA TGTGCCGGTA CACCCACCTC CACCCTTATA TCCTCTTCGC CCTGAACCTC CCCAGCCTCC CATTTCCTGG CGGGTGCGCG GGGGCGGCCC GGCGGAGACC ACCTGGCTGG GAGAAGGCGG AGGAGGCGAT GGCTACTATC CCTCGGGAGG CGCCTGGCCA GAGCCTGGTC GAGCCGGAGG AAGCCACCAG GAGCAGCCAC CATATCCTAG CTACAATTCT AACTATTGGA ATTCTACTGC GAGATCTAGG GCTCCTTACC CAAGTACATA TCCTGTAAGA CCAGAATTGC AAGGCCAGAG TTTGAATTCT TATACAAATG GAGCGTATGG TCCAACATAC CCCCCAGGCC CTGGGGCAAA TACTGCCTCA TACTCAGGGG CTTATTATGC ACCTGGTTAT ACTCAGACCA GTTACTCCAC AGAAGTTCCA AGTACTTACC GTTCATCTGG CAACAGCCCA ACTCCAGTCT CTCGTTGGAT CTATCCCCAG CAGGACTGTC AGACTGAAGC ACCCCCTCTT AGGGGGCAGG TTCCAGGATA TCCGCCTTCA CAGAACCCTG GAATGACCCT GCCCCATTAT CCTTATGGAG ATGGTAATCG TAGTGTTCCA CAATCAGGAC CGACTGTACG ACCACAAGAA GATGCGTGGG CTTCTCCTGG TGCTTATGGA ATGGGTGGCC GTTATCCCTG GCCTTCATCA GCGCCCTCAG CACCACCCGG CAATCTCTAC ATGACTGAAA GTACTTCACC ATGGCCTAGC AGTGGCTCTC CCCAGTCACC CCCTTCACCC CCAGTCCAGC AGCCCAAGGA TTCTTCATAC CCCTATAGCC AATCAGATCA AAGCATGAAC CGGCACAACT TTCCTTGCAG TGTCCATCAG TACGAATCCT CGGGGACAGT GAACAATGAT GATTCAGATC TTTTGGATTC CCAAGTCCAG TATAGTGCTG AGCCTCAGCT GTATGGTAAT GCCACCAGTG ACCATCCCAA CAATCAAGAT CAAAGTAGCA GTCTTCCTGA AGAATGTGTA CCTTCAGATG AAAGTACTCC TCCGAGTATT AAAAAAATCA TACATGTGCT GGAGAAGGTC CAGTATCTTG AACAAGAAGT AGAAGAATTT GTAGGAAAAA AGACAGACAA AGCATACTGG CTTCTGGAAG AAATGCTAAC CAAGGAACTT TTGGAACTGG ATTCAGTTGA AACTGGGGGC CAGGACTCTG TACGGCAGGC CAGAAAAGAG GCTGTTTGTA AGATTCAGGC CATACTGGAA AAATTAGAAA AAAAAGGATT ATGA
Additionnal Information
BAG4, BAG-4, SODD, BAG4, ATGD0089-10 µg, ATGD0089-20 µg, ATGD0089-50 µg, ATGD0089-100 µg, ATGD0089-250 µg, ATGD0089-500 µg, ATGD0089-1 mg, ATGD0089-10, ATGD0089-20, ATGD0089-50, ATGD0089-100, ATGD0089-250, ATGD0089-500, ATGD0089-1
Storage Conditions
Store the plasmid at -20C.
Formulation
Lyophilized
Scientific Category
Apoptosis
Omim
603884
NCBI Accession Number
NP_004865.1
Species
Human
Preparation
1. Centrifuge at 7000rpm for 1 minute.; ;2. Carefully open the vial and add 100 µL of sterile water to dissolve the DNA.; ; Each tube contains approximately 10 µg of lyophilized plasmid.
RNA Reference
NM_004874.3
DNA Size
1374bp
Vector Description
This shuttle vector contains the complete ORF. It is inseted BamH I to Xho I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector.

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