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DCK cDNA

CAT: 0112-ATGD0063-010Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGD0063-010Size:10 µg
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Description
DCK is a key enzyme in the salvage of deoxyribonucleosides and in the activation of clinically relevant nucleoside analogues. This protein is responsible for the 5'-phosphorylation of purine and pyrimidine deoxynucleosides to the corresponding monophosphates using ATP or uTP as phosphate donors. Deficiency of this enzyme activity is associated with resistance to antiviral and anticancer chemotherapeutic agents, whereas increased enzyme activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives.
Chromosomal Location
4q13.3-q21.1
Antigen Species
Human
Vector Type
PATGen (puc19-derived cloning vector)
Sequence
ATGGCCACCC CGCCCAAGAG AAGCTGCCCG TCTTTCTCAG CCAGCTCTGA GGGGACCCGC ATCAAGAAAA TCTCCATCGA AGGGAACATC GCTGCAGGGA AGTCAACATT TGTGAATATC CTTAAACAAT TGTGTGAAGA TTGGGAAGTG GTTCCTGAAC CTGTTGCCAG ATGGTGCAAT GTTCAAAGTA CTCAAGATGA ATTTGAGGAA CTTACAATGT CTCAGAAAAA TGGTGGGAAT GTTCTTCAGA TGATGTATGA GAAACCTGAA CGATGGTCTT TTACCTTCCA AACATATGCC TGTCTCAGTC GAATAAGAGC TCAGCTTGCC TCTCTGAATG GCAAGCTCAA AGATGCAGAG AAACCTGTAT TATTTTTTGA ACGATCTGTG TATAGTGACA GGTATATTTT TGCATCTAAT TTGTATGAAT CTGAATGCAT GAATGAGACA GAGTGGACAA TTTATCAAGA CTGGCATGAC TGGATGAATA ACCAATTTGG CCAAAGCCTT GAATTGGATG GAATCATTTA TCTTCAAGCC ACTCCAGAGA CATGCTTACA TAGAATATAT TTACGGGGAA GAAATGAAGA GCAAGGCATT CCTCTTGAAT ATTTAGAGAA GCTTCATTAT AAACATGAAA GCTGGCTCCT GCATAGGACA CTGAAAACCA ACTTCGATTA TCTTCAAGAG GTGCCTATCT TAACACTGGA TGTTAATGAA GACTTTAAAG ACAAATATGA AAGTCTGGTT GAAAAGGTCA AAGAGTTTTT GAGTACTTTG TGA
Additionnal Information
DCK, DCK, ATGD0063-10 µg, ATGD0063-20 µg, ATGD0063-50 µg, ATGD0063-100 µg, ATGD0063-250 µg, ATGD0063-500 µg, ATGD0063-1 mg, ATGD0063-10, ATGD0063-20, ATGD0063-50, ATGD0063-100, ATGD0063-250, ATGD0063-500, ATGD0063-1
Storage Conditions
Store the plasmid at -20C.
Formulation
Lyophilized
Scientific Category
Enzymes & Proteases
Omim
125450
NCBI Accession Number
NP_000779.1
Species
Human
Preparation
1. Centrifuge at 7000rpm for 1 minute.; ;2. Carefully open the vial and add 100 µL of sterile water to dissolve the DNA.; ; Each tube contains approximately 10 µg of lyophilized plasmid.
RNA Reference
NM_000788.2
DNA Size
783bp
Vector Description
This shuttle vector contains the complete ORF. It is inseted BamH I to Xho I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector.

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