Human STAT1 antibody

• Description:

  STAT1, also known as STAT91, is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. STAT1 is activated by peptide hormones, growth factors and cytokines, particularly cytokines of the interferon family.

• Product Name Alternative:

  Signal transducer and activator of transcription 1 91kDa, ISGF-3, STAT91, Transcription factor ISGF-3 components p91/p84, Signal transducer and activator of transcription 1, 91kDa

• Host:

  Mouse

• Antigen Species:

  Human

• Reactivity:

  Human

• Immunogen:

  Recombinant human STAT1 (1-712aa) purified from E. coli

• Clonality:

  Monoclonal

• Isotype:

  IgG1 κ

• Clone:

  AT1F4

• Conjugation:

  Unconjugated

• Applications:

  ELISA, WB

• Purification Method:

  By protein-G affinity chromatography

• Concentration:

  1 mg/mL (determined by BCA assay)

• Additionnal Information:

  STAT1, ATGA0546-10 µg, ATGA0546-20 µg, ATGA0546-50 µg, ATGA0546-100 µg, ATGA0546-250 µg, ATGA0546-500 µg, ATGA0546-1 mg, ATGA0546-10, ATGA0546-20, ATGA0546-50, ATGA0546-100, ATGA0546-250, ATGA0546-500, ATGA0546-1

• References & Citations:

  Farlik M., et al. (2010) Immunity. 33 (1) :25-34.

• Storage Conditions:

  Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

• Formulation:

  Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol

• Applications Notes:

  The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

• Scientific Category:

  Cancer

• NCBI Accession Number:

  NP_009330

• Uniprot Accession Number:

  P42224

• WB Description:

  The cell lysate (40ug) was resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human STAT1 antibody (1:1000) . Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.; ; Lane 1.: A431 cell lysate;