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Human STAT1 antibody

CAT: 0112-ATGA0546-100Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0112-ATGA0546-100Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
STAT1, also known as STAT91, is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. STAT1 is activated by peptide hormones, growth factors and cytokines, particularly cytokines of the interferon family.
Product Name Alternative
Signal transducer and activator of transcription 1 91kDa, ISGF-3, STAT91, Transcription factor ISGF-3 components p91/p84, Signal transducer and activator of transcription 1, 91kDa
Host
Mouse
Antigen Species
Human
Reactivity
Human
Immunogen
Recombinant human STAT1 (1-712aa) purified from E. coli
Clonality
Monoclonal
Isotype
IgG1 κ
Clone
AT1F4
Conjugation
Unconjugated
Applications
ELISA, WB
Purification Method
By protein-G affinity chromatography
Concentration
1 mg/mL (determined by BCA assay)
Additionnal Information
STAT1, ATGA0546-10 µg, ATGA0546-20 µg, ATGA0546-50 µg, ATGA0546-100 µg, ATGA0546-250 µg, ATGA0546-500 µg, ATGA0546-1 mg, ATGA0546-10, ATGA0546-20, ATGA0546-50, ATGA0546-100, ATGA0546-250, ATGA0546-500, ATGA0546-1
References & Citations
Farlik M., et al. (2010) Immunity. 33 (1) :25-34.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Applications Notes
The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.
Scientific Category
Cancer
NCBI Accession Number
NP_009330
Uniprot Accession Number
P42224
WB Description
The cell lysate (40ug) was resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human STAT1 antibody (1:1000) . Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.; ; Lane 1.: A431 cell lysate;

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