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Human PSMD11 antibody

CAT: 0112-ATGA0153-100Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0112-ATGA0153-100Size:100 µL
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Description
PSMD11 (Proteasome 26S non-ATPase subunit 11), also known as S9, Rpn6 or p44. 5, has multi-subunit protease complexes consisting of 20S subunits composed of four seven-numbered rings with two outer rings containing alpha subunits and two central rings composed of beta subunits, and 19S caps of 6 ATPase and 11 non-ATPase subunits. PSMD11 is the main proteolytic enzyme that functions in ATP-dependent degradation of ubiquitinated proteins.
Product Name Alternative
Proteasome (prosome, macropain) 26S subunit non-ATPase 11, S9, p44.5, MGC3844, Rpn6
Host
Mouse
Antigen Species
Human
Reactivity
Human
Immunogen
Recombinant human PSMD11 (1-422aa) purified from E. coli
Clonality
Monoclonal
Isotype
IgG1 κ
Clone
AT1F4
Conjugation
Unconjugated
Applications
ELISA, WB
Purification Method
By protein-G affinity chromatography
Concentration
1 mg/mL (determined by BCA assay)
Additionnal Information
PSMD11, ATGA0153-10 µg, ATGA0153-20 µg, ATGA0153-50 µg, ATGA0153-100 µg, ATGA0153-250 µg, ATGA0153-500 µg, ATGA0153-1 mg, ATGA0153-10, ATGA0153-20, ATGA0153-50, ATGA0153-100, ATGA0153-250, ATGA0153-500, ATGA0153-1
References & Citations
Sato Y, et al., (2009) Biochem Biophys Res Commun. 378 (4) :795-8.; ; Shibahara T, et al., (2002) Eur J Biochem. 269 (5) :1474-83.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Applications Notes
The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.
Scientific Category
Ubiquitination
NCBI Accession Number
NP_002806
Uniprot Accession Number
O00231
WB Description
The tissue lysate of mouse kidney (60ug) was resolved by SDS-PAGE, transferred to NC membrane and probed with anti-human PSMD11 (1:250) . Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system