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Recombinant human AHA1 protein

CAT: 0112-AHA0701-500Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0112-AHA0701-500Size:500 µg
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Description
The co-chaperone Aha1 (Activator of HSP90 ATPase-1) binds the middle domain of Hsp90 (amino acid 272-627) and is proposed to function as an ATPase-activating protein that competes with p23 and other co-chaperones for Hsp90 binding. Recombinant Aha1 was expressed in E. coli and purified by using conventional chromatography techniques.
Product Name Alternative
Activator of Hsp90 ATPase-1 (AHA1, 19-337), AHA1, AHSA1, Activator of Hsp90 ATPase protein 1, Hsp90 co-chaperone AHA1, Activator of Hsp90 ATPase-1 Activator of 90 kDa heat shock protein ATPase homolog 1, Activator of heat shock 90kDa protein ATPase homolog 1, C14orf3, HSPC322, p38
Expression System
E.coli
Antigen Species
Human
Tag
Non-Tagged
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 95% by SDS-PAGE
Molecular Weight
36.1 kDa (320aa) confirmed by MALDI-TOF
Additionnal Information
Activator of Hsp90 ATPase1, AHA1, Activator of Hsp90 ATPase-1, AHA1, Activator of Hsp90 ATPase-1 (AHA1, 19-337), Activator of Hsp90 ATPase protein 1, Hsp90 co-chaperone AHA1, Activator of Hsp90 ATPase-1 Activator of 90 kDa heat shock protein ATPase homolog 1, Activator of heat shock 90kDa protein ATPase homolog 1, AHA 1, AHSA 1, AHSA1, C14orf3, HSPC322, p38., AHA0701-10 µg, AHA0701-20 µg, AHA0701-50 µg, AHA0701-100 µg, AHA0701-250 µg, AHA0701-500 µg, AHA0701-1 mg, AHA0701-10, AHA0701-20, AHA0701-50, AHA0701-100, AHA0701-250, AHA0701-500, AHA0701-1
References & Citations
Meyer P., et al (2004) . EMBO 23 (6) : 1402-10; ; Siligardi G., et al (2004) . J Biol Chem. 270 (50) : 51989-98;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 2mM EDTA
Scientific Category
Heat Shock Proteins
NCBI Accession Number
NP_036243
Uniprot Accession Number
O95433
Species
Human
AA Sequence
MATNVNNWHW TERDASNWST DKLKTLFLAV QVQNEEGKCE VTEVSKLDGE ASINNRKGKL IFFYEWSVKL NWTGTSKSGV QYKGHVEIPN LSDENSVDEV EISVSLAKDE PDTNLVALMK EEGVKLLREA MGIYISTLKT EFTQGMILPT MNGESVDPVG QPALKTEERK AKPAPSKTQA RPVGVKIPTC KITLKETFLT SPEELYRVFT TQELVQAFTH APATLEADRG GKFHMVDGNV SGEFTDLVPE KHIVMKWRFK SWPEGHFATI TLTFIDKNGE TELCMEGRGI PAPEEERTRQ GWQRYYFEGI KQTFGYGARL

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