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Ethyl propiolate

CAT: 1139-623-47-2-01Size: 10 gDry Ice: NoHazardous: No
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CAT#:1139-623-47-2-01Size:10 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ethyl propiolate (CAS 623-47-2) is a high-purity terminal alkyne ester fine chemical with the molecular formula C5H6O2. It is a clear colorless to pale yellow liquid at room temperature, with good solubility in common organic solvents such as ethanol and ether. As a typical reactive acetylenic ester compound, it features active terminal alkyne and ester functional groups, possessing excellent chemical reactivity and derivatization performance, widely used in organic synthesis, pharmaceutical intermediate preparation and fine chemical customization fields.
Synonyms
Ethyl prop-2-ynoate, Ethyl propargylate, Ethyl 2-propynoate, Propiolic acid ethyl ester
HS Code
2916198090
Applications
1. Organic Synthetic Intermediate Manufacturing: Ethyl propiolate (CAS 623-47-2) serves as a core building block for various organic synthesis reactions, widely applied in the construction of heterocyclic compounds including pyrazole and pyridine derivatives, supporting the synthesis of complex fine chemical molecules. 2. Pharmaceutical Intermediate Synthesis: This reactive alkyne ester is an important raw material for the preparation of anti-inflammatory drugs and bioactive pharmaceutical intermediates, participating in multi-component synthetic reactions to construct drug molecular skeletons and improve product biological activity. 3. Fine Chemical Derivatization Reaction: Ethyl propiolate (CAS 623-47-2) is commonly used as a professional derivatization reagent for thiol and amine compounds, applied in chemical analysis, biological sample detection and functional molecule modification processes. 4. Catalytic Synthesis Research Reagent: It acts as a standard substrate for asymmetric alkynylation reactions and phosphine-catalyzed cyclic synthesis reactions, widely used in laboratory organic mechanism research and new synthetic process development.
Purity
≥98%
Molecular Formula
C5H6O2
Molecular Weight
98.10
Shelf Life
2 years under proper storage
Appearance
Clear colorless to pale yellow liquid
Grade
Fine Chemical Grade / Synthetic Reagent Grade
Density
0.968 g/mL at 25 °C (lit.)
Melting Point
9 °C
Boiling Point
120 °C (lit.)
EINECS
210-795-8