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(R) -3-Hydroxypyrrolidine

CAT: 1139-2799-21-5-01Size: 10 gDry Ice: NoHazardous: No
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CAT#:1139-2799-21-5-01Size:10 g
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Description
(R) -3-Hydroxypyrrolidine (CAS 2799-21-5) is a high-purity chiral pyrrolidine heterocyclic fine chemical with the molecular formula C4H9NO. It is a colorless transparent liquid at room temperature, with excellent water solubility and stable chemical properties under sealed and low-temperature conditions. This typical chiral alcohol amine compound has high optical purity and specific rotation characteristics, featuring active hydroxyl and secondary amine functional groups on the pyrrolidine ring. It possesses excellent molecular modifiability and stereoselective activity, serving as a core chiral building block widely used in pharmaceutical synthesis, asymmetric catalysis and fine chemical customization fields.
Synonyms
(R) -3-Pyrrolidinol, (R) - (+) -3-Hydroxypyrrolidine, (3R) -Pyrrolidin-3-ol, R-3-Hydroxypyrrolidine
HS Code
2933990090
Applications
1. Chiral Pharmaceutical Intermediate Synthesis: (R) -3-Hydroxypyrrolidine (CAS 2799-21-5) is a critical raw material for the synthesis of various chiral drugs, including central nervous system drugs, anti-inflammatory drugs and antiviral targeted drugs. Its unique chiral pyrrolidine skeleton can effectively improve the stereoselectivity and biological activity of drug molecules, ensuring the optical purity and pharmacological stability of finished pharmaceutical products. 2. Asymmetric Catalysis Research: This high-activity chiral compound is widely used as a chiral ligand and chiral auxiliary in asymmetric organic synthesis reactions. It can effectively regulate the stereochemical reaction process, improve reaction yield and chiral selectivity, and is commonly applied in the research and industrial optimization of high-selectivity catalytic synthesis processes. 3. Fine Chemical Custom Derivatization: (R) -3-Hydroxypyrrolidine (CAS 2799-21-5) contains reactive hydroxyl and secondary amine functional groups, supporting diversified chemical modification and derivatization reactions. It is widely used in the custom synthesis of high-value chiral heterocyclic fine chemicals, functional molecular materials and biochemical derivatives. 4. Biochemical and Medicinal Chemistry Research: It acts as a professional laboratory chiral reagent for chiral structure-activity relationship analysis, heterocyclic organic reaction mechanism exploration and new drug molecular screening, providing reliable raw material support for academic research and pharmaceutical process development.
Purity
≥98%
Molecular Formula
C4H9NO
Molecular Weight
87.12
Shelf Life
2 years under proper storage
Appearance
Colorless transparent liquid
Grade
Fine Chemical Grade / Pharmaceutical Intermediate Grade / Chiral Reagent Grade
Density
1.078 g/mL at 20 °C (lit.)
Melting Point
15 °C
Boiling Point
215-216 °C (lit.)
EINECS
Not available