Products for Research Use Only

Erdafitinib

CAT: 1139-1346242-81-6-01Size: 10 gDry Ice: NoHazardous: No
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CAT#:1139-1346242-81-6-01Size:10 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Erdafitinib (CAS: 1346242-81-6) is a potent, selective, and oral bioavailable pan-fibroblast growth factor receptor (FGFR) inhibitor. It is a high-value targeted pharmaceutical intermediate and anti-tumor active ingredient, which can effectively inhibit the kinase activity of FGFR1, FGFR2, FGFR3 and FGFR4. This compound blocks FGFR-mediated cell proliferation and angiogenesis signaling pathways, thereby inhibiting tumor cell growth and metastasis. It is widely used in pharmaceutical research, preclinical trials and industrial production of targeted anti-tumor drugs, with high biological specificity and stable chemical properties.
Synonyms
JNJ-42756493 Shipping & Payment Terms
HS Code
Not available
Applications
1. Targeted Anti-Tumor Drug API Production Erdafitinib (1346242-81-6) is a core active pharmaceutical ingredient for the production of FGFR-targeted anti-tumor drugs. It is mainly applied in the industrial manufacturing of therapeutic drugs for FGFR gene mutation-positive tumors such as advanced bladder cancer and solid tumors, serving as a key raw material for pharmaceutical production workshops. 2. Tumor Pharmacology Mechanism Research As a specific FGFR inhibitor reagent, Erdafitinib (CAS 1346242-81-6) is widely adopted in medical research institutions and university laboratories. It is used for exploring FGFR signaling pathway functions, tumor proliferation mechanisms, and drug resistance mechanisms, providing core experimental materials for oncology and pharmacological research projects. 3. Innovative Anti-Cancer Drug Development Erdafitinib (1346242-81-6) supports pre-clinical drug screening, formula optimization and efficacy verification. It is applicable to the research of combined anti-tumor regimens and new dosage form development, helping biotech and pharmaceutical enterprises accelerate the iteration and launch of innovative targeted anti-cancer drugs.
Purity
98% Min
Molecular Formula
C25H30N6O2
Molecular Weight
446.54
Shelf Life
2 years under proper storage
Appearance
Yellow to off-white crystalline powder
Grade
Pharmaceutical Grade, Research Grade
Density
1.20±0.1 g/cm3 at 20°C
Melting Point
136-140°C
EINECS
Not available

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