Larotrectinib Sulfate

Larotrectinib Sulfate (CAS: 1223405-08-0) is a highly selective oral tropomyosin receptor kinase (TRK) inhibitor. It is a targeted small-molecule pharmaceutical intermediate and active pharmaceutical ingredient, which can effectively inhibit the activity of TRKA, TRKB and TRKC proteins. This chemical compound blocks abnormal TRK fusion signaling pathways in organisms, thereby suppressing the proliferation and growth of tumor cells. It is widely recognized in the pharmaceutical and chemical industry for its high targeting specificity and low off-target toxicity, and is a core raw material for anti-tumor drug research, development and production.

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1. Pharmaceutical Anti-tumor Drug Synthesis Larotrectinib Sulfate (1223405-08-0) is the key raw material for the synthesis of larotrectinib anti-tumor drugs. It is mainly used in the industrial production of targeted therapeutic drugs for NTRK fusion-positive solid tumors, covering multiple malignant tumor treatments for adults and children, and is an essential intermediate in pharmaceutical chemical synthesis workshops. 2. Biomedical Laboratory Research As a standard TRK inhibitor reagent, Larotrectinib Sulfate (CAS 1223405-08-0) is widely used in university laboratories, pharmaceutical research institutions and biotech enterprises. It is applied in tumor mechanism research, drug efficacy verification, new drug formula optimization and pre-clinical trial research, providing core experimental materials for biomedical scientific research projects. 3. Pharmaceutical Raw Material Customization Production Larotrectinib Sulfate (1223405-08-0) can be customized for purity and packaging according to pharmaceutical production standards. It is applied in small-batch trial production and large-scale industrial mass production of targeted anti-cancer APIs, meeting the production and R&D needs of different pharmaceutical enterprises.

98% Min

C21H24F2N6O6S

526.52

2 years under proper storage

White to off-white powder

Pharmaceutical Grade, Research Grade

1.58±0.1 g/cm3 at 20°C

218-222°C