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3-Chlorophenylboronic acid

CAT: 1139-63503-60-6-01Size: 10 gDry Ice: NoHazardous: No
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Description
3-Chlorophenylboronic acid (CAS: 63503-60-6) is an aromatic boronic acid derivative, belonging to the class of organoboron compounds. It has a chemical formula of C6H6BClO2 and a molecular weight of 156.38, characterized by a benzene ring substituted with a chlorine atom (-Cl) at the 3-position (meta-substitution) and a boronic acid group (-B (OH) 2) at the 1-position. 3-Chlorophenylboronic acid (CAS: 63503-60-6) is a white to off-white crystalline powder with slight hygroscopicity, slightly soluble in cold water, soluble in hot water, ethanol, methanol, acetone and organic solvents containing water, and exhibits typical chemical properties of boronic acids, such as susceptibility to hydrolysis and participation in Suzuki cross-coupling reactions.
Synonyms
M-Chlorophenylboronic acid,3-Chlorobenzeneboronic acid, (3-Chlorophenyl) boronic acid,3-Chloro-benzeneboronic acid, m-Chlorobenzeneboronic acid,3-Chlorophenylboronic acid
Applications
1. Pharmaceutical Intermediate: 3-Chlorophenylboronic acid (CAS: 63503-60-6) is widely used as a key intermediate in pharmaceutical synthesis, mainly for the preparation of aromatic heterocyclic drugs, anti-tumor drugs, anti-inflammatory agents and antiviral drugs, leveraging its boronic acid group to participate in Suzuki cross-coupling, Chan-Lam coupling and other reactions to construct carbon-carbon bonds. 2. Chemical Intermediate: 3-Chlorophenylboronic acid (CAS: 63503-60-6) serves as an important intermediate in organic synthesis, used for the preparation of various substituted benzene derivatives, organoboron compounds and fine chemical intermediates through substitution, oxidation, reduction and coupling reactions. 3. Material Intermediate: 3-Chlorophenylboronic acid (CAS: 63503-60-6) is applied in the synthesis of functional materials, such as organic semiconductors, liquid crystals and specialty polymers, due to its aromatic structure and adjustable electronic properties, helping to improve the thermal stability and mechanical properties of the final products. 4. Fine Chemicals: 3-Chlorophenylboronic acid (CAS: 63503-60-6) is utilized in the production of fine chemicals, including specialty reagents, analytical standards, organic dyes and pesticides intermediates, leveraging its stable chemical properties and specific reactivity of boronic acid groups.
Purity
≥98%
Molecular Formula
C6H6BClO2
Molecular Weight
156.38
Storage Conditions
Store in a cool, dry, well-ventilated area away from light, heat and oxidizing agents. Keep container tightly closed to prevent moisture absorption. Avoid contact with water, strong bases and oxidants. Store at room temperature (15-30 °C) for short-term, 2-8 °C for long-term preservation.
Appearance
White to off-white crystalline powder
Density
1.28 g/cm3 (predicted)
Melting Point
227-231 °C (lit.)
EINECS
263-984-6