2-Fluoro-3-nitrobenzoic acid

2-Fluoro-3-nitrobenzoic acid (CAS: 317-46-4) is an organic aromatic compound belonging to the nitrobenzoic acid derivative family, with a benzene ring as the core structure, substituted at the 2-position with a fluorine atom and at the 3-position with a nitro group, and a carboxylic acid group (-COOH) at the 1-position. It is a trifunctional aromatic compound with unique chemical reactivity, derived from the synergistic effect of the carboxylic acid, nitro and fluorine functional groups. It is a key intermediate in organic synthesis and pharmaceutical production due to its stable chemical properties and controllable reactivity, especially its utility in nucleophilic aromatic substitution and nitro group reduction reactions.

2-Fluoro-3-nitrobenzoic acid, 3-Nitro-2-fluorobenzoic acid, o-Fluoro-m-nitrobenzoic acid, 2-Fluoro-3-nitro-benzoic acid, 3-Nitro-o-fluorobenzoic acid

1. Organic Synthesis Intermediate: 2-Fluoro-3-nitrobenzoic acid (CAS: 317-46-4) is widely used as an intermediate in organic synthesis reactions, especially nucleophilic aromatic substitution (S_NAr) and nitro group reduction reactions. It serves as a key raw material for the synthesis of complex aromatic compounds, fluorinated derivatives and heterocyclic compounds, providing multiple reactive sites (carboxylic acid, nitro, fluorine) for efficient synthetic reactions, and laying a foundation for the construction of diverse molecular scaffolds. 2. Pharmaceutical Intermediate: 2-Fluoro-3-nitrobenzoic acid (CAS: 317-46-4) is a versatile pharmaceutical intermediate, widely applied in the research and development and production of active pharmaceutical ingredients (APIs) . Its fluorine atom can enhance the metabolic stability and bioavailability of drug molecules, while the nitro group can be reduced to a primary amine for further structural modification, making it a key raw material for the synthesis of anti-tumor, anti-inflammatory and antiviral drugs. 3. Fine Chemical Raw Material: 2-Fluoro-3-nitrobenzoic acid (CAS: 317-46-4) is used in the production of fine chemicals, such as organic dyes, pigments and specialty additives. Its aromatic structure and functional groups can improve the color fastness and stability of dyes and pigments, and it is also used as a modifier in the production of specialty resins and coatings to optimize product performance. 4. Laboratory Research Reagent: 2-Fluoro-3-nitrobenzoic acid (CAS: 317-46-4) is used as a standard reagent and model compound in laboratory research, widely applied in the study of reaction mechanisms of nitrobenzoic acid derivatives, fluorinated aromatic compounds and the development of new synthetic methodologies for pharmaceutical intermediates.

≥98.0%

C7H4FNO4

185.11

2 years under proper storage

Pale yellow to light brown crystalline powder

Industrial Grade, Research Grade, Pharmaceutical Grade

1.583 g/cm3

128-132°C