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N-PENTYLBORONIC ACID

CAT: 1139-4737-50-2-01Size: 1 EachDry Ice: NoHazardous: No
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Description
N-PENTYLBORONIC ACID (CAS: 4737-50-2) is a classic linear alkyl boronic acid fine chemical intermediate with high reaction activity and stable chemical properties. Different from aromatic boronic acids, this product features a straight-chain pentyl alkyl structure, presenting excellent lipophilicity and moderate water solubility. It effectively avoids excessive hydrolysis and protodeboronation under conventional experimental conditions, with stable room-temperature stability and low impurity residual rate. As a common aliphatic boron reagent, it has good compatibility with various organic solvents, and can efficiently participate in cross-coupling and alkyl derivatization reactions, widely applied in organic synthetic chemistry, pharmaceutical intermediate modification and fine chemical functional optimization.
Synonyms
N-Pentylboronic acid, Pentylboronic acid, 1-Pentaneboronic acid, N-Pentyl boronic acid
HS Code
2931900090
Applications
1. Suzuki-Miyaura Coupling Reactions: N-PENTYLBORONIC ACID (CAS: 4737-50-2) is a universal aliphatic boron coupling reagent for classic Suzuki cross-coupling reactions. It can efficiently introduce linear n-pentyl alkyl fragments into aromatic, heterocyclic and aliphatic molecular frameworks, construct long-chain alkyl-substituted complex organic compounds, reduce side reactions such as self-coupling and deboronation, and significantly improve reaction yield and product structural purity. 2. Aliphatic Pharmaceutical Intermediate Synthesis: This 4737-50-2 product serves as an important alkylated building block for small-molecule drug intermediates. The linear pentyl group can effectively adjust the lipophilicity, metabolic rate and bioavailability of drug molecules. It is widely used in the structural modification and synthesis of anti-inflammatory, antibacterial, lipid-regulating and analgesic drug intermediates, supporting the R&D and industrial production of new aliphatic derivative drugs. 3. Fine Chemical Alkyl Modification: High-purity N-PENTYLBORONIC ACID is commonly used for alkyl functional modification of high-value fine chemicals. It can graft stable linear pentyl chains onto target molecular skeletons, optimize the physical and chemical properties such as molecular solubility, stability and surface activity, and enrich the product diversity of fine chemical derivatives. 4. Laboratory Boron Chemistry Research: It is a standard aliphatic boronic acid reagent in chemical laboratories, used for the development of new alkyl coupling processes, verification of boron chemical reaction mechanisms, and synthetic route optimization of long-chain aliphatic compounds, providing stable and high-purity raw material support for scientific research and process pilot tests.
Purity
≥98%
Molecular Formula
C5H13BO2
Molecular Weight
115.97
Shelf Life
2 years under proper storage
Appearance
White to off-white crystalline solid powder
Grade
Fine chemical grade, Synthetic intermediate grade, Laboratory reagent grade
Density
0.905±0.06 g/cm3 (Predicted)
Melting Point
94 °C (lit.)
Boiling Point
207.9±23.0 °C (Predicted)
EINECS
Not available