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6-HYDROXY-3-PYRIDINEBORONIC ACID

CAT: 1139-903899-13-8-01Size: 10 gDry Ice: NoHazardous: No
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CAT#:1139-903899-13-8-01Size:10 g
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Description
6-HYDROXY-3-PYRIDINEBORONIC ACID (CAS: 903899-13-8) is a high-purity pyridine-based heterocyclic boronic acid fine chemical. It features a unique molecular structure integrating hydroxyl functional group and boronic acid group on the pyridine ring, with stable chemical skeleton, moderate reactivity and good solubility in organic solvents such as DMF and DMSO. This compound is sensitive to high temperature and humid environment, prone to hydrolysis and structural decomposition under improper storage conditions. 6-HYDROXY-3-PYRIDINEBORONIC ACID (903899-13-8) serves as a critical heterocyclic synthetic building block, widely utilized in pharmaceutical intermediate synthesis, biomedical compound development and fine organic derivatization reactions.
Synonyms
6-Hydroxypyridin-3-ylboronic acid, 6-Hydroxypyridine-3-boronic acid, 2-Hydroxy-5-pyridineboronic acid, 5-Borono-2-hydroxypyridine
HS Code
2933399990
Applications
1. Pharmaceutical Intermediate Synthesis 6-HYDROXY-3-PYRIDINEBORONIC ACID (CAS: 903899-13-8) is a core raw material for the synthesis of anti-viral and anti-tumor drug intermediates. It is mainly used for the preparation of non-nucleoside HCV NS5B polymerase inhibitors and mTOR inhibitor intermediates, supporting the R&D and pilot production of high-activity biomedical small-molecule drugs. 2. Suzuki Cross-Coupling Reaction Manufacturing 6-HYDROXY-3-PYRIDINEBORONIC ACID (903899-13-8) acts as a high-efficiency heterocyclic boronic acid coupling reagent. It can undergo high-selectivity Suzuki cross-coupling reactions with halogenated aromatic and heterocyclic compounds under mild catalytic conditions, efficiently constructing complex pyridine-containing functional molecular skeletons for fine chemical customization. 3. Biomedical Functional Compound Development 6-HYDROXY-3-PYRIDINEBORONIC ACID (CAS: 903899-13-8) is widely applied in the development of targeted therapeutic compounds. Its dual active hydroxyl and boronic acid functional groups can effectively adjust the biological activity and molecular affinity of drug molecules, providing key structural modification sites for new biomedical compound research. 4. Laboratory Organic Synthetic Research 6-HYDROXY-3-PYRIDINEBORONIC ACID (903899-13-8) is a standard high-purity laboratory research reagent. It is commonly used for the exploration of heterocyclic boronic acid reaction mechanisms, optimization of cross-coupling synthetic routes and structural modification research of nitrogen-containing heterocyclic compounds in academic and industrial laboratories.
Purity
≥98%
Storage Conditions
Store at -20 °C under inert nitrogen atmosphere in dry, sealed and dark ventilated environment, avoid moisture, high temperature and air exposure to prevent decomposition and activity attenuation
Shelf Life
2 years under proper storage
Appearance
White to off-white crystalline solid
Grade
Research Grade, Fine Chemical Grade, Pharmaceutical Intermediate Grade
Density
1.36±0.1 g/cm3