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NSC 145669

CAT: 0804-HY-116799Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-116799Size:1 Each
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Description
NSC 145669 is an inhibitor for tubulin polymerization with IC50 of 1.7 μM. NSC 145669 exhibits cytotoxicity in cancer cells and reveals antileukemic efficacy in mice[1].
CAS Number
31785-60-1
UNSPSC
12352005
Target
Microtubule/Tubulin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nsc-145669.html
Smiles
O=C1NC(NC2=C1C=CC=C2)C3=C4C=CC=CC4=CC=C3
Molecular Formula
C18H14N2O
Molecular Weight
274.32
References & Citations
[1]Hamel E, et al., Antitumor 2,3-dihydro-2- (aryl) -4 (1H) -quinazolinone derivatives. Interactions with tubulin. Biochem Pharmacol. 1996 Jan 12;51 (1) :53-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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