5-Bromo-2-fluorophenol

5-Bromo-2-fluorophenol (CAS 112204-58-7) is a high-purity di-substituted halogenated phenolic fine chemical intermediate. This product exists as colorless to light yellow liquid or off-white crystalline solid at room temperature, featuring a stable benzene ring structure co-modified with bromo, fluoro and hydroxyl functional groups. It possesses excellent chemical stability and diversified reaction activity, supporting substitution, condensation and cross-coupling reactions. With moderate polarity and good solubility in conventional organic solvents, 5-Bromo-2-fluorophenol (CAS 112204-58-7) is a core halogenated phenolic building block widely applied in pharmaceutical synthesis, agrochemical preparation and fine organic derivatization.

1. Pharmaceutical Intermediate Synthesis: 5-Bromo-2-fluorophenol (CAS 112204-58-7) serves as a critical halogenated phenolic intermediate for new drug R&D. Its unique bromine-fluorine co-substituted structure can optimize drug molecular lipophilicity and metabolic stability, and is commonly used in the synthesis of antibacterial, anti-inflammatory and targeted small-molecule pharmaceutical intermediates. 2. Agrochemical Compound Preparation: 5-Bromo-2-fluorophenol (CAS 112204-58-7) is widely used in the preparation of high-efficiency pesticide and insecticide derivatives. It acts as a key reaction raw material for constructing fluorine-containing aromatic agrochemical molecular skeletons, improving the efficacy and environmental adaptability of agrochemical products. 3. Suzuki Cross-Coupling Reaction Derivatization: 5-Bromo-2-fluorophenol (CAS 112204-58-7) has high-activity bromine reactive sites, which can efficiently participate in palladium-catalyzed Suzuki cross-coupling reactions. It is used for the synthesis of multi-functional substituted fluorinated aromatic compounds in fine organic synthesis. 4. Functional Fine Chemical Modification: 5-Bromo-2-fluorophenol (CAS 112204-58-7) can undergo diversified structural modification through hydroxyl and halogen functional groups. It is applied to the customization and production of high-value fluorine-containing phenolic fine chemicals and biochemical functional materials.

≥98%

C6H4BrFO

191.00

2 years under proper storage

Colorless to light yellow liquid or off-white crystalline solid

Synthetic Grade, Pharmaceutical Intermediate Grade, Laboratory Grade

1.764±0.06 g/cm3

60-80°C

53°C / 0.2 mmHg