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1-Ethyl-3-iodopyrazole

CAT: 1139-1202781-34-7-01Size: 1 EachDry Ice: NoHazardous: No
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Description
1-Ethyl-3-iodopyrazole (CAS 1202781-34-7) is a high-purity halogen-substituted pyrazole fine chemical. This compound features a pyrazole ring skeleton with ethyl substitution at the N1 position and iodine substitution at the C3 position, possessing stable molecular structure, excellent organic solubility and high cross-coupling reaction activity. It is light and heat sensitive, prone to decomposition under strong light and high temperature conditions, requiring low-temperature sealed dark storage to maintain chemical stability. The unique iodo-ethyl dual-substituted pyrazole structure provides high reaction selectivity and molecular modification potential. 1-Ethyl-3-iodopyrazole (CAS 1202781-34-7) serves as a core heterocyclic building block, widely applied in pharmaceutical intermediate synthesis, organic cross-coupling reactions and fine chemical derivatization for laboratory R&D and industrial batch production.
Applications
1. Suzuki Cross-Coupling Reaction Synthesis: 1-Ethyl-3-iodopyrazole (CAS 1202781-34-7) is a high-efficiency iodo-substituted pyrazole monomer for palladium-catalyzed Suzuki-Miyaura cross-coupling reactions. The active carbon-iodine bond enables efficient selective coupling reactions, supporting the synthesis of complex multi-substituted pyrazole derivatives and high-value heterocyclic fine chemicals. 2. Heterocyclic Pharmaceutical Intermediate Manufacturing: 1-Ethyl-3-iodopyrazole (CAS 1202781-34-7) is a key customized intermediate for new heterocyclic drug development. Its stable N-ethyl substituted pyrazole skeleton can undergo multi-step structural modification, which is widely used in the synthesis of anti-inflammatory, antiviral and small-molecule targeted drug intermediates. 3. Fine Chemical Derivatization Processing: 1-Ethyl-3-iodopyrazole (CAS 1202781-34-7) supports diversified derivatization reactions including amination, alkylation and cyclization. It can be used to prepare various functional pyrazole compounds, meeting the customized production needs of fine chemical and new material industries. 4. Organic Synthetic Route Research: 1-Ethyl-3-iodopyrazole (CAS 1202781-34-7) acts as a standard high-purity experimental reagent for halogenated pyrazole chemistry research. It provides a typical structural model for studying the reaction mechanism of iodo-heterocyclic compounds, supporting the development of green and efficient organic synthetic routes.
Purity
≥98%
Molecular Formula
C5H7IN2
Molecular Weight
222.03
Shelf Life
2 years under proper storage
Appearance
Light yellow transparent liquid
Grade
Laboratory Grade, Industrial Grade, Pharmaceutical Grade
Density
1.87±0.1 g/cm3
Boiling Point
286.3±32.0°C at 760 mmHg