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2,5-Difluorophenylboronic acid

CAT: 1139-193353-34-3-01Size: 1 EachDry Ice: NoHazardous: No
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CAT#:1139-193353-34-3-01Size:1 Each
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Description
2,5-Difluorophenylboronic acid (CAS 193353-34-3) is a high-purity difluoro-substituted aromatic boronic acid fine chemical. This compound features a stable benzene ring skeleton with 2,5-difluoro substituents and active boronic acid functional groups, presenting typical moisture-sensitive chemical properties. It maintains stable molecular structure and excellent cross-coupling reaction activity under low-temperature inert sealed storage, and has good solubility in polar organic solvents such as methanol. The dual fluorine substitution structure endows the product with excellent molecular lipophilicity, stable chemical performance and high reaction selectivity. 2,5-Difluorophenylboronic acid (CAS 193353-34-3) serves as a core difluorinated aromatic synthetic building block, widely applied in pharmaceutical intermediate customization, fluorinated fine chemical derivatization and organic synthetic reaction research in laboratory and industrial production fields.
Applications
1. Fluorinated Aromatic Cross-Coupling Reaction Synthesis: 2,5-Difluorophenylboronic acid (CAS 193353-34-3) is a key monomer for palladium-catalyzed Suzuki-Miyaura cross-coupling reactions. Its unique 2,5-difluoro substituted benzene structure optimizes reaction stability and product purity, effectively reducing by-product generation, and is widely used for industrial batch synthesis of high-purity difluorinated biaryl fine chemical intermediates. 2. Pharmaceutical Intermediate Customized Manufacturing: 2,5-Difluorophenylboronic acid (CAS 193353-34-3) is an essential modular intermediate for new drug research and development. The difluoro functional structure can effectively adjust drug molecular metabolic stability and biological targeting activity, supporting structural modification and customized synthesis of antibacterial, anti-inflammatory and anti-tumor small-molecule pharmaceutical intermediates. 3. High-Value Fluorinated Fine Chemical Derivatization: 2,5-Difluorophenylboronic acid (CAS 193353-34-3) acts as a critical industrial precursor for diversified fluorinated aromatic derivatives. The active boronic acid functional group supports multi-step substitution, oxidation and condensation reactions, enabling the preparation of high-end functional fine chemicals and biochemical analytical reagents. 4. Laboratory Organic Synthesis Research: 2,5-Difluorophenylboronic acid (CAS 193353-34-3) is a standard high-purity synthetic reagent for organic chemistry research. With stable batch quality and unique difluorinated aromatic reaction characteristics, it is widely used for organic reaction mechanism verification and new functional compound development in scientific research projects.
Purity
99%
Molecular Formula
C6H5BF2O2
Molecular Weight
157.91
Shelf Life
2 years under proper storage
Appearance
White to pale yellow crystalline powder
Grade
Laboratory Grade, Industrial Grade, Pharmaceutical Grade
Density
1.35±0.1 g/cm3
Melting Point
105-110°C
Boiling Point
271.3±50.0°C at 760 mmHg