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4- (Hydroxymethyl) phenylboronic acid

CAT: 1139-59016-93-2-01Size: 10 gDry Ice: NoHazardous: No
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CAT#:1139-59016-93-2-01Size:10 g
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Description
4- (Hydroxymethyl) phenylboronic acid (CAS: 59016-93-2) is a high-purity hydroxymethyl-functionalized aromatic boronic acid fine chemical. The molecular structure consists of a phenylboronic acid skeleton modified with a para-hydroxymethyl active group, featuring mild reaction activity, excellent hydrophilic and organic solvent solubility, and stable chemical properties under conventional synthetic conditions. This monosubstituted boronic acid has low hydrolysis rate and high coupling selectivity, supporting efficient and low-side-reaction organic synthesis. 4- (Hydroxymethyl) phenylboronic acid (59016-93-2) acts as a versatile bifunctional building block, extensively used in fine organic synthesis, pharmaceutical intermediate modification and functional molecular customization for industrial and laboratory applications.
Synonyms
4-Hydroxymethylphenylboronic acid, (4- (Hydroxymethyl) phenyl) boronic acid, p-Hydroxymethylphenylboronic acid, 4-Boronobenzyl alcohol
HS Code
29319000
Applications
1. Versatile Suzuki Cross-Coupling Synthesis 4- (Hydroxymethyl) phenylboronic acid (CAS: 59016-93-2) is a universal monomer for high-efficiency Suzuki-Miyaura cross-coupling reactions. The retained hydroxymethyl functional group enables post-coupling structural derivation, which can be further etherified, esterified or oxidized to construct complex functional molecules, meeting industrial batch synthesis requirements of high-purity substituted aromatic fine chemicals. 2. Pharmaceutical Intermediate Derivatization 4- (Hydroxymethyl) phenylboronic acid (59016-93-2) is a critical precursor for the preparation of hydroxymethyl-substituted pharmaceutical intermediates. The active hydroxymethyl and boronic acid dual reactive sites optimize molecular binding activity, supporting the R&D and scale-up production of anti-tumor, antibacterial and anti-inflammatory targeted drug intermediates. 3. Functional Biochemical Probe Preparation 4- (Hydroxymethyl) phenylboronic acid (CAS: 59016-93-2) is widely applied in customized synthesis of biochemical detection probes and biological functional materials. Its balanced hydrophilicity and lipophilicity improve molecular solubility in mixed solvents, while dual reactive groups provide accurate modification sites for probe molecular assembly and functional optimization.
Purity
≥98%
Features & Benefits
Lingzhiyue technology provide comprehensive product support, including: ✅ Competitive price, stable bulk supply to meet large-scale procurement needs. ✅ Custom Solutions: Custom Purity & Packaging to match different application scenarios and procurement requirements. ✅ Full test reports: COA, HPLC, NMR, MSDS and professional technical support for safe use and quality confirmation. ✅ Fast response within 12 hours to answer inquiries and solve problems in a timely manner, ensuring efficient communication. If you are looking for a reliable manufacturer or need the latest price, please feel free to send us an inquiry. Request COA & Quotation:[email protected]
Storage Conditions
Store at 2-8 °C in dry, sealed, dark and inert nitrogen environment, away from moisture, high temperature and strong oxidants to prevent boronic acid hydrolysis and hydroxymethyl group oxidation
Shelf Life
2 years under proper storage
Appearance
White to off-white crystalline powder
Grade
Research Grade, Fine Chemical Grade
Density
1.27±0.1 g/cm3
Melting Point
210-214 °C