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2,5-Dibromothiazole

CAT: 1139-4175-78-4Size: 1 EachDry Ice: NoHazardous: No
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CAT#:1139-4175-78-4Size:1 Each
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Description
2,5-Dibromothiazole (CAS 4175-78-4) is a high-activity halogenated thiazole heterocyclic fine chemical. The molecular structure is based on a 1,3-thiazole ring with bromine atoms substituted at the 2 and 5 positions, possessing two active halogen reaction sites for efficient organic derivatization and cross-coupling reactions. 2,5-Dibromothiazole (CAS 4175-78-4) features stable heterocyclic skeleton and excellent chemical reactivity, commercially supplied as white to off-white crystalline solid. It is a vital foundational intermediate widely used in pharmaceutical synthesis, pesticide development and laboratory organic synthetic research.
Synonyms
2,5-Dibromo-1,3-thiazole, 2,5-dibromothiazole
HS Code
2934100000
Applications
1. Pharmaceutical Heterocyclic Intermediate: 2,5-Dibromothiazole (CAS 4175-78-4) serves as a core building block for synthesizing thiazole-based small-molecule drugs, including anti-inflammatory, antibacterial, antiviral and anti-tumor agents. The dibromo-substituted thiazole skeleton can effectively improve the biological activity and target affinity of drug molecules. 2. Organic Coupling Reaction Substrate: This difunctional brominated thiazole compound is widely applied in Suzuki, Heck, Sonogashira and Buchwald-Hartwig cross-coupling reactions. 2,5-Dibromothiazole (CAS 4175-78-4) provides dual active sites for constructing complex fused heterocyclic compounds and functional organic molecular frameworks. 3. Agrochemical Intermediate Synthesis: Used for the derivatization synthesis of high-efficiency thiazole pesticides, fungicides and insecticides, helping to optimize product biological activity and environmental compatibility in crop protection fields. 4. Laboratory Synthetic Chemistry Research: It acts as a standard experimental reagent for thiazole functional modification, heterocyclic reaction mechanism exploration and new bioactive compound screening, supporting academic laboratory research and industrial process optimization.
Purity
≥98%
Molecular Formula
C3HBr2NS
Molecular Weight
242.92
Shelf Life
2 years under proper storage
Appearance
White to off-white crystalline solid
Grade
Fine Chemical Grade, Pharmaceutical Intermediate Grade, Research Grade
Density
2.23±0.1 g/cm3 (Predicted)
Melting Point
40–42 °C
Boiling Point
226.3±20.0 °C at 760 mmHg