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(R) -2-methylpiperazine

CAT: 1139-75336-86-6-01Size: 1 EachDry Ice: NoHazardous: No
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Description
(R) -2-methylpiperazine (CAS 75336-86-6) is a high-purity chiral aliphatic nitrogen heterocyclic fine chemical. This compound is a single R-configured chiral piperazine derivative with a methyl-substituted six-membered dinitrogen heterocyclic structure, featuring stable chiral configuration, excellent solubility in water and polar organic solvents, and moderate chemical activity. It is prone to moisture absorption and oxidation when exposed to air, requiring low-temperature sealed dry storage to maintain chiral purity and structural stability. As a critical chiral building block, (R) -2-methylpiperazine (CAS 75336-86-6) is widely applied in chiral drug intermediate synthesis, asymmetric catalytic reaction research and fine chemical chiral derivatization for laboratory R&D and industrial standardized production.
Applications
1. Chiral Pharmaceutical Intermediate Synthesis: (R) -2-methylpiperazine (CAS 75336-86-6) serves as a core chiral precursor for the preparation of high-purity pharmaceutical intermediates. Its stable R-chiral structure effectively improves the stereoselectivity of synthetic reactions, and it is commonly used in the manufacturing of central nervous system drugs, anti-infective drugs and cardiovascular drug intermediates with strict chiral purity requirements. 2. Asymmetric Catalytic Reaction Research: (R) -2-methylpiperazine (CAS 75336-86-6) acts as a classic chiral amine ligand and auxiliary reagent for asymmetric catalytic reactions. It can regulate the stereoselectivity of organic synthesis reactions, supporting the development and optimization of new green asymmetric synthetic routes in fine chemical research. 3. Chiral Fine Chemical Derivatization: (R) -2-methylpiperazine (CAS 75336-86-6) is widely used for the derivatization of high-value chiral fine chemicals. The active secondary amine groups on the piperazine ring can undergo alkylation, acylation and condensation reactions to synthesize various customized chiral heterocyclic compounds, meeting the differentiated procurement needs of fine chemical enterprises. 4. Organic Molecular Sieve and Material Modification: (R) -2-methylpiperazine (CAS 75336-86-6) can be used as a chiral modifier for porous organic materials and molecular sieves. It endows conventional porous materials with chiral recognition ability, which is applied in chiral separation and asymmetric adsorption fields of new functional materials.
Purity
≥98%
Molecular Formula
C5H12N2
Molecular Weight
100.16
Shelf Life
2 years under proper storage
Appearance
White to pale yellow crystalline solid or block
Grade
Laboratory Grade, Industrial Grade, Pharmaceutical Grade
Density
0.93 g/cm3
Melting Point
91-93°C
Boiling Point
155-156°C at 760 mmHg