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2-Ethoxy-4-fluorophenylboronic acid

CAT: 1139-480438-58-2Size: 1 EachDry Ice: NoHazardous: No
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Description
2-Ethoxy-4-fluorophenylboronic acid (CAS 480438-58-2) is a high-purity fluoroalkoxy-substituted aromatic boronic acid fine chemical. The molecular structure contains ethoxy and fluorine functional groups on the benzene ring with boronic acid active groups, featuring moderate moisture sensitivity, stable chemical properties and good solubility in conventional polar organic solvents.2-Ethoxy-4-fluorophenylboronic acid (CAS 480438-58-2) is a crucial fluorine-containing synthetic building block, widely applied in cross-coupling reaction synthesis, pharmaceutical intermediate customization and fine chemical derivation for industrial production and laboratory research.
Applications
1. Suzuki Cross-Coupling Reaction Synthesis: 2-Ethoxy-4-fluorophenylboronic acid (CAS 480438-58-2) is a core reactive monomer for palladium-catalyzed Suzuki cross-coupling reactions. The dual substitution of ethoxy and fluorine optimizes molecular reaction activity and selectivity, effectively improving the synthesis efficiency of high-value fluorine-containing biaryl intermediates in fine chemical industrial production. 2. Pharmaceutical Intermediate Custom Synthesis: 2-Ethoxy-4-fluorophenylboronic acid (CAS 480438-58-2) serves as an important modular intermediate for new drug R&D. The fluorine-containing alkoxy structure enhances the metabolic stability and biological activity of drug molecules, which is commonly used in the customized synthesis of anti-inflammatory, antibacterial and targeted small-molecule drug intermediates. 3. Fluorine-Containing Fine Chemical Derivation: 2-Ethoxy-4-fluorophenylboronic acid (CAS 480438-58-2) acts as a key precursor for high-end fluorine fine chemicals. It can be used for structural modification and derivation of aromatic compounds, improving the lipophilicity and chemical stability of finished fine chemical products. 4. Laboratory Synthetic Process Optimization: 2-Ethoxy-4-fluorophenylboronic acid (CAS 480438-58-2) is a standard high-purity laboratory reagent. With stable batch purity and controllable reactive characteristics, it is widely used for reaction mechanism verification and process optimization of fluoroalkoxy phenylboronic acid compounds in scientific research experiments.
Purity
98%
Molecular Formula
C8H10BFO3
Molecular Weight
183.97
Shelf Life
2 years under proper storage
Appearance
White crystalline powder
Grade
Laboratory Grade, Industrial Grade
Density
1.25±0.1 g/cm3
Melting Point
136-141°C
Boiling Point
309.8±52.0°C at 760 mmHg