Benzocaine

• UNSPSC Description:

  Benzocaine shares a common receptor with all othe rLAs in the voltage-gated Na+ channel, with an IC50 of 0.8 mM tested with a potential of +30 mV.

• Target Antigen:

  Bacterial; Sodium Channel

• Type:

  Reference compound

• Related Pathways:

  Anti-infection;Membrane Transporter/Ion Channel

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/Benzocaine.html

• Purity:

  99.98

• Solubility:

  DMSO : ≥ 100 mg/mL|H2O : 2 mg/mL (ultrasonic;warming;heat to 60°C)

• Smiles:

  O=C(OCC)C1=CC=C(N)C=C1

• Molecular Weight:

  165.192

• References & Citations:

  [1]Wang GK et al. A common local anesthetic receptor for benzocaine and etidocaine in voltage-gated mu1 Na+ channels. Pflugers Arch. 1998 Jan;435(2):293-302.|[2]Di Croce D et al. Drug action of benzocaine on the sarcoplasmic reticulum Ca-ATPase from fast-twitch skeletal muscle. Naunyn Schmiedebergs Arch Pharmacol. 2015 Nov;388(11):1163-70.|[3]Davis JA, et al. Benzocaine-induced methemoglobinemia attributed to topical application of the anesthetic in several laboratory animal species. Am J Vet Res. 1993 Aug;54(8):1322-6.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  RT, protect from light

• Clinical Information:

  Launched

• CAS Number:

  94-09-7