ROR1 rabbit pAb

• Background:

  Receptor tyrosine kinase like orphan receptor 1 (ROR1) Homo sapiens This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2012]

• Product Name Alternative:

  Tyrosine-protein kinase transmembrane receptor ROR1 (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1)

• Gene ID:

  4919

• Swiss Prot:

  Q01973

• Cross Reactivity:

  Human; Mouse; Rat

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB

• Dilution:

  WB 1:500-2000

• Buffer:

  Liquid in PBS containing 50% glycerol, and 0.10% sodium azide.

• Molecular Weight:

  105

• Storage Conditions:

  -20°C/1 year

• Protein Weight:

  105