TYK2 rabbit pAb

• Background:

  Tyrosine kinase 2 (TYK2) Homo sapiens This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq, Jul 2008]

• Product Name Alternative:

  Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)

• Gene ID:

  7297

• Swiss Prot:

  P29597

• Cross Reactivity:

  Human; Mouse; Rat

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB

• Dilution:

  WB 1:500-2000

• Buffer:

  Liquid in PBS containing 50% glycerol, and 0.05% sodium azide.

• Storage Conditions:

  -20°C/1 year