ZNRF2 Polyclonal Antibody

CAT: 1027-RA36632-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:1027-RA36632-01Size:50 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Domain:The RING-type zinc finger domain is required for E3 ligase activity., function:May play a role in the establisment and maintenance of neuronal transmission and plasticity via its ubiquitin ligase activity. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates., pathway:Protein modification; protein ubiquitination., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Contains 1 RING-type zinc finger., subcellular location:Present in presynaptic plasma membranes in neurons., subunit:Interacts with UBE2N., tissue specificity:Highly expressed in the brain, with higher expression during development than in adult. Expressed also in mammary glands, testis, colon and kidney.
Product Name Alternative
ZNRF2; RNF202; E3 ubiquitin-protein ligase ZNRF2; Protein Ells2; RING finger protein 202; Zinc/RING finger protein 2
Gene ID
223082
Swiss Prot
Q8NHG8
Cross Reactivity
Human; Mouse
Clonality
Polyclonal
Source
Rabbit
Applications
IHC-p; IF/ICC; ELISA
Dilution
Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Conditions
-20°C/1 year

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