UB2D1 Polyclonal Antibody

• Background :

  Ubiquitin conjugating enzyme E2 D1 (UBE2D1) Homo sapiens The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]

• Gene ID :

  7321

• Swiss Prot :

  P51668

• Cross Reactivity :

  Human; Rat; Mouse

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Dilution :

  WB 1:500-2000 ELISA 1:5000-20000

• Buffer :

  Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

• Molecular Weight :

  16

• Storage Conditions :

  -20°C/1 year

• Protein Weight :

  16