Tyk 2 Polyclonal Antibody

• Background:

  Tyrosine kinase 2 (TYK2) Homo sapiens This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq, Jul 2008]

• Product Name Alternative:

  TYK2; Non-receptor tyrosine-protein kinase TYK2

• Gene ID:

  7297

• Swiss Prot:

  P29597

• Cross Reactivity:

  Human; Mouse; Monkey

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB; IHC-p; IF/ICC; ELISA

• Dilution:

  Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

• Buffer:

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Molecular Weight:

  134

• Storage Conditions:

  -20°C/1 year

• Protein Weight:

  134