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TRIPC Polyclonal Antibody

CAT: 1027-RA35544-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1027-RA35544-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Function:Component of PA700, an ATP-dependent multisubunit protein that activates the proteolytic activities of the multifunctional proteinase (20S proteasome) of the 26S complex. Specifically interacts with the ligand binding domain of the thyroid hormone receptor (in a thyroid hormone T3-independent manner) and with retinoid X receptor (RXR) . Could be E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates., miscellaneous:A cysteine residue is required for ubiquitin-thioester formation., pathway:Protein modification; protein ubiquitination., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Belongs to the UPL family. K-HECT subfamily., similarity:Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain., similarity:Contains 1 WWE domain., subunit:PA700 is composed of at least 16 distinct peptides ranging from 20-112 kDa.
Gene ID
9320
Swiss Prot
Q14669
Cross Reactivity
Human; Rat; Mouse
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Buffer
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Molecular Weight
219
Storage Conditions
-20°C/1 year
Protein Weight
219

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