TRIF Polyclonal Antibody

• Background:

  Toll like receptor adaptor molecule 1 (TICAM1) Homo sapiens This gene encodes an adaptor protein containing a Toll/interleukin-1 receptor (TIR) homology domain, which is an intracellular signaling domain that mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. This protein is involved in native immunity against invading pathogens. It specifically interacts with toll-like receptor 3, but not with other TLRs, and this association mediates dsRNA induction of interferon-beta through activation of nuclear factor kappa-B, during an antiviral immune response. [provided by RefSeq, Jan 2012]

• Product Name Alternative:

  TIR domain-containing adapter molecule 1 (TICAM-1; Proline-rich, vinculin and TIR domain-containing protein B; Putative NF-kappa-B-activating protein 502H; Toll-interleukin-1 receptor domain-containing adapter protein inducing interferon beta; TIR domain-containing adapter protein inducing IFN-beta)

• Gene ID:

  148022

• Swiss Prot:

  Q8IUC6

• Cross Reactivity:

  Human; Rat; Mouse

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB; IHC-p; IF (paraffin section) ; ELISA

• Dilution:

  WB 1:500-2000, IHC-p 1:50-200 ELISA 1:10000-20000

• Buffer:

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Molecular Weight:

  80

• Storage Conditions:

  -20°C/1 year

• Protein Weight:

  80