SOD2 Polyclonal Antibody

• Background:

  Superoxide dismutase 2, mitochondrial (SOD2) Homo sapiens This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 1. [provided by RefSeq, Apr 2016]

• Product Name Alternative:

  SOD2; Superoxide dismutase [Mn], mitochondrial; YM3421

• Gene ID:

  6648

• Swiss Prot:

  P04179

• Cross Reactivity:

  Human; Mouse; Rat

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB; IHC-p; IF (paraffin section)

• Dilution:

  Western Blot: 1/500 - 1/2000.IHC-p:1:50-300. Not yet tested in other applications.

• Buffer:

  PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

• Molecular Weight:

  22

• Storage Conditions:

  -20°C/1 year

• Protein Weight:

  22