SNX13 rabbit pAb

• Background:

  This gene encodes a PHOX domain- and RGS domain-containing protein that belongs to the sorting nexin (SNX) family and the regulator of G protein signaling (RGS) family. The PHOX domain is a phosphoinositide binding domain, and the SNX family members are involved in intracellular trafficking. The RGS family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. The RGS domain of this protein interacts with G alpha (s), accelerates its GTP hydrolysis, and attenuates G alpha (s) -mediated signaling. Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor. Because of its bifunctional role, this protein may link heterotrimeric G protein signaling and vesicular trafficking. [provided by RefSeq, Jul 2008]

• Product Name Alternative:

  Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1)

• Gene ID:

  23161

• Swiss Prot:

  Q9Y5W8

• Cross Reactivity:

  Human; Mouse

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB

• Dilution:

  WB 1:500-2000

• Buffer:

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.277% sodium azide.

• Molecular Weight:

  105

• Storage Conditions:

  -20°C/1 year

• Protein Weight:

  105