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PZP Polyclonal Antibody

CAT: 1027-RA34313-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1027-RA34313-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Function:Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced) . Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase., similarity:Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family., subunit:Homotetramer, which consists of two pairs of disulfide-linked chains., tissue specificity:Plasma. Prominent constituent of late-pregnancy sera.
Swiss Prot
P20742
Cross Reactivity
Human; Rat; Mouse
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Buffer
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Molecular Weight
163
Storage Conditions
-20°C/1 year
Protein Weight
163

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