PPIG Polyclonal Antibody

• Background:

  Catalytic activity:Peptidylproline (omega=180) = peptidylproline (omega=0) ., domain:The RS domain is required for the interaction with the phosphorylated C-terminal domain of RNA polymerase II., enzyme regulation:Cyclosporin A (CsA) -sensitive., function:PPIases accelerate the folding of proteins., function:PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides., function:PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. May be implicated in the folding, transport, and assembly of proteins. May play an important role in the regulation of pre-mRNA splicing., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Belongs to the cyclophilin-type PPIase family., similarity:Contains 1 PPIase cyclophilin-type domain., subcellular location:Colocalizes with RNA splicing factors at nuclear speckles., subunit:Interacts with CLK1, PNN and with the phosphorylated C-terminal domain of RNA polymerase II., tissue specificity:Ubiquitous.

• Gene ID:

  9360

• Swiss Prot:

  Q13427

• Cross Reactivity:

  Human; Rat; Mouse

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB; ELISA

• Dilution:

  WB 1:500-2000 ELISA 1:5000-20000

• Buffer:

  Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

• Molecular Weight:

  82

• Storage Conditions:

  -20°C/1 year

• Protein Weight:

  82