PCNT Polyclonal Antibody

• Background:

  Pericentrin (PCNT) Homo sapiens The protein encoded by this gene binds to calmodulin and is expressed in the centrosome. It is an integral component of the pericentriolar material (PCM) . The protein contains a series of coiled-coil domains and a highly conserved PCM targeting motif called the PACT domain near its C-terminus. The protein interacts with the microtubule nucleation component gamma-tubulin and is likely important to normal functioning of the centrosomes, cytoskeleton, and cell-cycle progression. Mutations in this gene cause Seckel syndrome-4 and microcephalic osteodysplastic primordial dwarfism type II. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]

• Gene ID:

  5116

• Swiss Prot:

  O95613

• Cross Reactivity:

  Human; Mouse

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  IHC-p; IF (paraffin section)

• Dilution:

  IHC-p 1:50-300

• Buffer:

  Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

• Molecular Weight:

  366

• Storage Conditions:

  -20°C/1 year

• Protein Weight:

  366