PCNT Polyclonal Antibody
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PCNT Polyclonal Antibody
Background :
Pericentrin (PCNT) Homo sapiens The protein encoded by this gene binds to calmodulin and is expressed in the centrosome. It is an integral component of the pericentriolar material (PCM) . The protein contains a series of coiled-coil domains and a highly conserved PCM targeting motif called the PACT domain near its C-terminus. The protein interacts with the microtubule nucleation component gamma-tubulin and is likely important to normal functioning of the centrosomes, cytoskeleton, and cell-cycle progression. Mutations in this gene cause Seckel syndrome-4 and microcephalic osteodysplastic primordial dwarfism type II. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]Gene ID :
5116Swiss Prot :
O95613Cross Reactivity :
Human; MouseClonality :
PolyclonalSource :
RabbitApplications :
IHC-p; IF (paraffin section)Dilution :
IHC-p 1:50-300Buffer :
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.Molecular Weight :
366Storage Conditions :
-20°C/1 yearProtein Weight :
366

